老年钙化性主动脉瓣狭窄与冠心病的关系  

Relationship between senile calcific aortic stenosis and coronary heart disease

作　　者：孙仕怀 王琦光[2] 朱鲜阳[2] 崔春生[2] 孟立立[2] 王建铭[2] 魏鑫[1] Department of Cardiology Liaoning Medical University Jinzhou 121001 Liaoning China;2.Department of Congenital Heart Disease General Hospital Shenyang Military Area Command Shenyang 110016

机构地区：[1]辽宁医学院心内科,辽宁锦州121001 [2]沈阳军区总医院先心病内科,辽宁沈阳110016

出　　处：《心脏杂志》2017年第2期192-194,197,共4页Chinese Heart Journal

摘　　要：目的探讨老年钙化性主动脉瓣狭窄(senile calcific aortic stenosis,SCAS)与冠心病的关系。方法收集沈阳军区总医院收治的SCAS患者173例。所有患者均行常规检查与冠状动脉造影检查,明确冠脉病变并行Gensini评分,进行相关统计分析。结果将所有患者按跨主动脉瓣平均压差分为轻、中、重3组。经冠脉造影检查明确29例并发冠心病,冠心病阳性率在动脉粥样硬化(AS)重度狭窄组为25%>AS中度狭窄组(16%)>AS轻度狭窄组(8%)。3组间冠心病阳性率存在显著差异(P<0.05),具有统计学意义。此外,3组平均Gensini评分分别为0.906、1.430和5.905,随着主动脉瓣狭窄程度的增加,评分也具有增加趋势,表明二者具有相关性。结论 SCAS与冠心病间存在相关性。AIM To explore the relationship between senile calcific aortic stenosis （SCAS） and coronary heart disease （CHD）. METHODS One hundred and seventy-three patients with SCAS in our hospital were enrolled. Each patient underwent routine examination and coronary angiography. To identify the condition of the coronary artery and Gensini score, statistical analysis was performed. RESULTS Among the 173 patients, 78 were males and 95 females, aged 60-77 years （65.67±6.6 years）. Patients were divided into three groups： mild, moderate and severe SCAS according to the average transvalvular pressure of aortic valve. There were 29 patients with CHD according to the results of coronary angiography. The positive rates of CHD in the severe SCAS group, moderate SCAS group and mild SCAS group were 25%, 16%, and 8%, respectively, with statistical difference among the three groups （P=0.036）. Average Gensini scores in the mild SCAS group, moderate SCAS group and SCAS severe group were, respectively, 0.906, 1.430 and 5.905, increasing with the higher degree of SCAS. CONCLUSION There is a relationship between SCAS and CHD. The positive rate and severity of CHD have an increasing tendency with the increase in the degree of SCAS.

关 键 词：主动脉瓣狭窄 钙化性 冠状动脉疾病 危险因素 

分 类 号：R541.4[医药卫生—心血管疾病]