Investigation of L/D-threonine substituted L-serine octamer ions by mass spectrometry and infrared photodissociation spectroscopy  

作　　者：Juan Ren Yi-Yun Wang Ru-Xia Fenga Xiang-Lei Kong 

机构地区：[1]The State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China [2]Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin 300071, China

出　　处：《Chinese Chemical Letters》2017年第3期537-540,共4页中国化学快报（英文版）

基　　金：Financial support from the National Natural Science Foundation of China(No.21475065)

摘　　要：Threonine-substituted serine octamer ions were generated by electrospray ionization（ESI） and investigated by mass spectrometry and infrared photodissociation（IRPD） spectroscopy. IRPD spectra of[L-Ser_7＋ L/D-Thr_1]H~＋and [L-Ser_6＋ L/D-Thr_2]H~＋were obtained in the range of 2700–3600 cm^（-1）. Chiral differentiation was achieved by comparing their IRPD spectra. The main difference located in the range of 3300–3500 cm^（-1）. And the results indicate the substitution of L-Ser by D-Thr could weaken the intermolecular H-bonds and loosen the original structures of serine octamers.Threonine-substituted serine octamer ions were generated by electrospray ionization（ESI） and investigated by mass spectrometry and infrared photodissociation（IRPD） spectroscopy. IRPD spectra of[L-Ser_7＋ L/D-Thr_1]H~＋and [L-Ser_6＋ L/D-Thr_2]H~＋were obtained in the range of 2700–3600 cm^（-1）. Chiral differentiation was achieved by comparing their IRPD spectra. The main difference located in the range of 3300–3500 cm^（-1）. And the results indicate the substitution of L-Ser by D-Thr could weaken the intermolecular H-bonds and loosen the original structures of serine octamers.

关 键 词：IRPD spectroscopy Threonine Serine octamer Chiral differentiation Mass spectrometry 

分 类 号：O636.9[理学—高分子化学]