A minor arcutine-type C20-diterpenoid alkaloid iminium constituent of“fu zi”  

作　　者：Xian-Hua Meng Zhi-Bo Jiang Qing-Lan Guo Jian-Gong Shi 

机构地区：[1]State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China

出　　处：《Chinese Chemical Letters》2017年第3期588-592,共5页中国化学快报（英文版）

基　　金：Financial support from the National Natural Science Foundation of China(NNSFC;Nos.81630094 and 30825044)

摘　　要：A rare arcutine-type C_（20）-diterpenoid alkaloid, named aconicarmicharcutinium A and obtained as hydroxide（1） and trifluoroacetate（1a）, was characterized as a minor constituent of ＂fu zi＂（the lateral roots of Aconitum carmichaelii）. The structures of 1 and 1a were elucidated by comprehensive analysis of spectroscopic data including^（19）F and 2D NMR experiments. Compounds 1 and 1a represent the first examples of the arcutine-type C_（20）-diterpenoid alkaloid iminium.A rare arcutine-type C_（20）-diterpenoid alkaloid, named aconicarmicharcutinium A and obtained as hydroxide（1） and trifluoroacetate（1a）, was characterized as a minor constituent of ＂fu zi＂（the lateral roots of Aconitum carmichaelii）. The structures of 1 and 1a were elucidated by comprehensive analysis of spectroscopic data including^（19）F and 2D NMR experiments. Compounds 1 and 1a represent the first examples of the arcutine-type C_（20）-diterpenoid alkaloid iminium.

关 键 词：Aconitum carmichaelii Ranunculaceae Arcutine-type C_（20）-diterpenoid alkaloid iminium Aconicarmicharcutinium A 

分 类 号：O629.3[理学—有机化学]