乳腺癌术后长期存活者阈下抑郁状况与生命质量的相关性研究  

The study of the subthreshold depression and their quality of life for long-term survivors after breast cancer surgery

作　　者：吕利明[1] 高慧[2] 程海英[1] Lyu Liming Gao Hui Cheng Haiying(Nursing College of Shandong University of Traditional Chinese Medicine, Jinan 250355, Chin)

机构地区：[1]山东中医药大学护理学院,济南250355 [2]山东中医药大学第二附属医院血液净化中心

出　　处：《中国实用护理杂志》2017年第4期259-264,共6页Chinese Journal of Practical Nursing

基　　金：2015年山东省高等学校人文社会科学研究项目（J15WC02）;山东省软科学研究计划（2012RKB14138）

摘　　要：目的 了解乳腺癌术后长期存活者阈下抑郁发生状况及其影响因素,探讨其与生命质量的关系.方法 采用自编一般情况调查表、流调用抑郁自评量表（CES-D）、汉密尔顿抑郁量表、乳腺癌患者生命质量测定量表对山东中医药大学第二附属医院乳腺科门诊就诊的210例乳腺癌术后长期存活者进行阈下抑郁和生命质量问卷调查,并分析其相关性.结果 乳腺癌术后长期存活者阈下抑郁发生率为46.67%（98/210）;年龄≤50岁（OR=5.627、2.662,P〈0.01）、婚姻状况为未婚、离异或丧偶（OR=5.087,P〈0.01）、在职情况为无业、病休或退休（OR=2.077,P〈0.05）、较低个人收入水平（〈3000元/月）（OR=3.375,P〈0.01）是阈下抑郁发生的危险因素;阈下抑郁患者的生命质量得分低于非抑郁患者（t=-6.653--2.926,P〈0.01）;患者CES-D与生命质量得分呈负相关（β=-0.362--0.132）.结论 乳腺癌术后长期存活者阈下抑郁发生率较高,低龄、非在婚、非在职及较低个人收入水平可增加患者阈下抑郁发生的危险性,阈下抑郁可降低患者的生命质量,应重视阈下抑郁的早期发现和干预,以提高患者的生命质量.Objective To investigate the subthreshold depression for long-term survivors after breast cancer surgery and its effect on their quality of life （QOL）. Methods The self-made general questionnaire, Centre for Epidemiological Studies Depression Scale （CES- D）, Hamihon Rating Scale for Depression and Functional Assessment of Cancer Therapy- Breast were used to investigate the subthreshold depression and its effect on their QOL for 210 long-term survivors after breast cancer surgery. The difference in general conditions and score of QOL between the subthreshold depression and non-subthreshold depression groups was also compared. Results The subthreshold depression with incidence rate of 46.67%（98/210） was observed for the log-term survivors after breast cancer surgery in this study. The results indicated that the age （≤50） （OR=5.627, 2.662,P〈0.01）, marriage （unmarried, divorced or widowed） （OR=5.087, P〈0.01）, employment （unemployed, sick leave or retired） （OR=2.077,P〈0.05） and low income （〈3000 RMB/month） （OR=3.375,P〈0.01） were the key factors that led to the occurrence of subthreshold depression. The score of QOL for the subthreshold depression group were lower than those of the non-subthreshold depression group （t=-6.653--2.926,P〈0.01）, and had a significantly negative correlation with score of depression and QOL （β=-0.362--0.132）. Conclusions A high incidence rate of subthreshold depression for long-term survivors after breast cancer surgery was observed. The incidence rate of subthreshold depression increased for the patients with younger age, low income,unmarried or unemployment. Due to their low QOL, attentions should be paid to the early detection and early prevention for the long-term survivors with subthreshold depression after breast cancer surgery.

关 键 词：生活质量 乳腺肿瘤 阈下抑郁 长期存活患者 

分 类 号：R473.73[医药卫生—护理学]