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作 者:宁桂军[1] 王旭霞[2] 刘世文[3] 朱玉英[3] 张秉玲[2] 张晓曙[2] 李艺星[1] 尹遵栋[1] 杨维中[1]
机构地区:[1]中国疾病预防控制中心免疫规划中心,北京100050 [2]甘肃省疾病预防控制中心,甘肃兰州730000 [3]白银市疾病预防控制中心,甘肃白银730900
出 处:《中国疫苗和免疫》2017年第1期18-21,12,共5页Chinese Journal of Vaccines and Immunization
摘 要:目的了解白银市5岁以下儿童社区获得性肺炎(Community acquired pneumonia,CAP)的疾病负担。方法制定病例定义,采用多阶段抽样,在疫苗接种单位调查5岁以下儿童,了解CAP的发病情况、就医直接和间接花费。结果白银市5岁以下儿童CAP发病密度估计为0.074/人年;城区、农村儿童分别为0.084/人年、0.069/人年;0岁组最低(0.044/人年);1岁组最高(0.088/人年)。每例CAP总费用平均为6 215.9元,其中直接和间接费用分别为4 462.8元和1 753.1元。2016年白银市5岁以下儿童数为97 303人,CAP的总经济负担估计为4 423.7万元。结论白银市5岁以下儿童CAP疾病负担较高;应进一步开展相关疫苗纳入免疫规划的成本效益分析。Objective To analyze the disease burden of community acquired pneumonia(CAP) among children under 5 years old in Baiyin.Methods A previously-developed case definition and a multi-stage sampling method were used to investigate children under 5 years old in vaccination units to determine CAP incidence and direct and indirect medical costs.Results The incidence density of CAP among children under 5 years old in Baiyin was 0.074 per person-year,with 0.084 per person-year in urban areas and 0.069 per person-year in rural areas.The lowest incidence(0.044 per person-year) was in the less-than-one-year old group,and the highest incidence(0.088 per person-year) was in the 1 year old group.The average cost per case was 6 215.9 RMB,including 4 462.8 RMB of direct costs and 1 753.1RMB of indirect costs.Among the 97 303 children under 5 years old in Baiyin in 2016,the estimated total cost of CAP was 44.24 million RMB.Conclusions The disease burden of CAP among children under 5 years old is high in Baiyin.The potential economic benefits of introducing relevant vaccines into immunization program should be further evaluated.
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