8760例住院患者人血白蛋白临床使用分析与评价  

Analysis and Evaluation of Human Serum Albumin Use in 8 760 Inpatients

作　　者：曾晶[1,2] 徐萍[1,2] 王清[1,2] 朱艳[1,2] 原海燕[1,2] 肖轶雯[1,2] Andrew Cave Hoan Linh Banh 

机构地区：[1]中南大学湘雅二医院药学部,长沙410011 [2]中南大学临床药学研究所,长沙410011 [3]阿尔伯塔大学医学与牙科学院/家庭医学部

出　　处：《中国药房》2017年第8期1027-1030,共4页China Pharmacy

基　　金：湖南省药学会生物专项基金资助项目(No.xy2015008)

摘　　要：目的:为人血白蛋白临床合理使用提供参考。方法:回顾性调查我院2014年1-12月使用人血白蛋白的住院患者病例,统计患者一般资料、用药前血清白蛋白水平、用药量、费用、用药原因等信息,并进行分析。结果:人血白蛋白使用人数最多的8个科室共8 760例患者纳入研究,占全院使用人血白蛋白住院患者的64%。其中,男性5 244例(占59.9%),女性3 516例(占40.1%),患者年龄主要集中在>30~60岁(占52.6%)。白蛋白使用人数最多的科室为普通外科(2 588例)和心血管外科(2 348例)。以国内说明书作为参照标准时,该院有8 210例(约93.7%)患者符合适应证,低蛋白血症为最常见的用药指征(占35.6%)。重症监护治疗病房人均使用量最高(152.5 g),普通外科总用药金额最高(13 334 396.4元),传染科人均使用疗程最长(10.7 d)。结论:我院存在人血白蛋白不合理使用情况,科室间使用情况存在差异。应加强对人血白蛋白使用的监督,建立合理的用药评估体系,以促进用药规范,实现医疗资源合理分配。OBJECTIVE： To provide references for rational use of human serum albumin. METHODS： The inpatients receiving human serum albumin in the hospital during Jan.-Dec. 2014 were investigated retrospectively and analyzed in respects of general information of patients, serum albumin level before medication, drug dosage, drug cost and reasons. RESULTS： Eight thousand seven hundred and sixty patients from top 8 departments in the list of the number of patients of human serum albumin were included in the study, accounting for 64 % of total. There were 5 244 male （59.9%） and 3 516 female （40.1% ）; patient＇s age mainly ranged 〉 30-60 year-old （52.6%）. The number of patients of albumin was the largest in general surgery department （2 588 cases） and cardiovascular surgery department （2 348 cases）. Referring to domestic package inserts, 8 210 patients （about 93.7% ） were in accordance with indications, and hypoproteinemia was the most common medication indication （ 35.6 % ）. The drug dosage per capita of ICU was the highest （152.5 g） ; total drug cost was the highest in general surgery department （13 334 396.4 yuan） ; treatment course per capita of infection disease department was the longest （10.7 d）. CONCLUSION： There is irrational use of human serum albumin in our hospital and difference of drug use among departments. It is necessary to strengthen human serum albumin use monitoring and establish rational medication evaluation system so as to promote standard drug use and realize rational distribution of medical resources.

关 键 词：人血白蛋白 临床应用 用量 金额 适应证 

分 类 号：R977[医药卫生—药品] R969.3[医药卫生—药学]