氯胺酮和异丙酚联合瑞芬太尼用于剖宫产全麻诱导的临床对比分析  

Clinical Comparative Analysis on Ketamine and Propofol Combined with Remifentanil in Induction of General Anesthesia for Cesarean Section

作　　者：陈文雄[1] 邓志海[1] 欧阳文博[1] 

机构地区：[1]广东省肇庆市第一人民医院,广东肇庆526000

出　　处：《临床医学工程》2017年第3期351-352,共2页Clinical Medicine & Engineering

摘　　要：目的探讨氯胺酮和异丙酚联合瑞芬太尼用于剖宫产全麻诱导的临床效果。方法选取我院2014年6月至2016年6月选择剖宫产的80例产妇,随机分为对照组和治疗组各40例。对照组仅用氯胺酮进行麻醉诱导,治疗组采用氯胺酮和异丙酚联合瑞芬太尼进行麻醉诱导。对比两组新生儿情况以及手术过程产妇心率和平均动脉压的变化。结果两组产妇T_0、T_1时刻的心率和平均动脉压比较差异无统计学意义(P>0.05)。T_2到T4时段,对照组的心率、平均动脉压升高,治疗组波动相对平稳(P<0.05)。治疗组的新生儿Apgar评分以及血气指标PaCO_2、PaO_2均优于对照组(P<0.05)。结论临床采用氯胺酮和异丙酚联合瑞芬太尼进行剖宫产全麻诱导,手术期间产妇的心率、血压平稳,新生儿呼吸抑制弱。Objective To explore the clinical effect of ketamine and propofol combined with remifentanil in induction of general anesthesia for cesarean section. Methods 80 cases of puerpera with cesarean section admitted to our hospital from June 2014 to June 2016 were selected and randomly divided into control group and treatment group, with 40 cases in each group. The control group received ketamine for anesthesia induction, while the treatment group received ketamine and propofol combined with remifentanil for anesthesia induction. The neonatal condition and changes of heart rate and mean arterial pressure of puerpera during operation were compared between two groups. Results No statistical difference was found in the heart rate and mean arterial pressure of puerpera at T0 and T1 between two groups （P〉0.05）. From T2 to T4, the heart rate and mean arterial pressure of control group increased, but the fluctuations of treatment group were relatively stable （P〈0.05）. The neonatal Apgar score and blood gas indicators （PaCO2 and PaO2） were better than those of control group （P〈0.05）. Conclusions Ketamine and propofol combined with remifentanil in induction of general anesthesia for cesarean section has stable heart rate and blood pressure ofpuerpera during operation, and week respiratory depression of neonates.

关 键 词：全麻诱导 瑞芬太尼 剖宫产 氯胺酮 异丙酚 

分 类 号：R614.2[医药卫生—麻醉学]