鹿蹄草属植物化学成分、药理活性与质量控制研究进展  

Chemical constituents,biological activities and quality control of plants from genus Pyrola

作　　者：赵泽丰 吴妮[1] 田雪[1] 付有兰 张强[1] 何希瑞[1,2] 魏潇洋 曾敏[1] 白亚军[3] 郑晓晖[1] ZHAO Ze-feng WU Ni TIAN Xue FU You-lan ZHANG Qiang HE Xi-rui WEI Xiao-yang ZENG Min BAI Ya-jun ZHENG Xiao-hui(Key Laboratory of Resource Biology and Biotechnology in Western China, ,Northwest University, Ministry of Education Xi＇ an 710069, China Hong-Hui Hospital, College of Medicine, Xi＇an Jiaotong University, Xi＇an 710054, China College of Chemistry and Materials Science, Northwest University, Xi＇an 710069, China)

机构地区：[1]西北大学西部资源生物与现代生物技术重点实验室,陕西西安710069 [2]西安交通大学医学院附属红会医院,陕西西安710054 [3]西北大学化学与材料科学学院,陕西西安710069

出　　处：《中国中药杂志》2017年第4期618-627,共10页China Journal of Chinese Materia Medica

基　　金：长江学者和创新团队发展基金滚动项目(IRT_15R55);国家自然科学基金青年科学基金项目(2013YQ170525)

摘　　要：鹿蹄草属植物广泛分布于北温带各区域,主要含有醌类、酚苷、萜类、黄酮类及挥发油类化合物,具有抗氧化、抗肿瘤、抑菌、抗心肌缺血、抗炎等多种药理活性。该文在广泛检索文献基础上对鹿蹄草属植物的化学成分,药理活性与质量控制研究进展进行综述,为鹿蹄草资源的合理利用提供依据。Plants from the genus Pyrola are widely distributed in North Temperate zone. The quinones,phenol glycosides,terpenoids,flavonoids and volatile oil compounds have been identified from these plants. The in vivo and in vitro studies have shown that the genus Pyrola plants exhibit a wide range of pharmacological properties,including antioxidant,antitumor,antibacterial,anti-ischemia and anti-inflammatory activities. Based on analysis of the literature of the genus Pyrola plant,this review summarized the research on chemical constituents,pharmacology and quality control in recent years which can provide evidences for further investigation on the genus Pyrola plants.

关 键 词：鹿蹄草 化学成分 药理活性 质量控制 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]