钨钴硬质合金职业接触者血清KL-6水平的分析  

Analysis on KL-6 level of serum in occupational exposure workers of tungsten- cobalt carbide alloy

作　　者：王乐乐[1] 张雪艳[2] 王忠旭[2] 唐仕川[3] 彭仁和 胡双球 何卫红 孙康 贾光[1] 

机构地区：[1]北京大学公共卫生学院,北京100191 [2]中国疾病预防控制中心职业卫生与中毒控制所,北京100050 [3]北京市劳动保护科学研究所,北京100054 [4]湖南省职业病防治院,湖南长沙410007 [5]株洲市职业病防治中心,湖南株洲412000

出　　处：《中国安全生产科学技术》2017年第2期5-9,共5页Journal of Safety Science and Technology

基　　金：卫生公益性行业科研专项(201402021)

摘　　要：为了探讨硬质合金职业接触及相关因素对劳动者血清KL-6水平的影响,选取硬质合金接触组407名劳动者,非硬质合金作业的对照组297名劳动者,对所有研究对象进行基本信息问卷调查,检测各岗位钨、钴浓度,竞争法酶联免疫吸附实验检测研究对象血清KL-6水平。结果表明:接触硬质合金粉尘可增加外周血清KL-6水平;钴可能是硬质合金粉尘致肺损伤的主要危害因素;年龄、吸烟对血清KL-6水平无显著影响;饮酒可增加硬质合金粉尘接触者KL-6水平。To investigate the influence caused by occupational exposure and relative factors of carbide alloy on the KL- 6level of serum in workers,407 workers in the group with exposure to carbide alloy were selected,as well as 297 workers in the control group without exposure to carbide alloy operation. The questionnaire survey of basic information was conducted on all the research objects,the concentrations of tungsten and cobalt in operation posts were detected,and the KL- 6 level of serum in all the research objects were detected by the competitive ELISA. The results showed that the carbide alloy dust exposure increases the KL- 6 level of peripheral serum. Cobalt may be the major hazardous factor that causes lung injury of carbide alloy dust. Age and smoking have no significant effects on the KL- 6 level of serum,but drinking increases the KL- 6 level of workers with exposure to carbide alloy dust.

关 键 词：硬质合金 KL-6 肺损伤 

分 类 号：R135[医药卫生—劳动卫生]