高频rTMS刺激M1区治疗带状疱疹后神经痛的短期疗效观察  

Short-term curative effect observation on high frequency rTMS stimulating M1 area treatment on postherpetic neuralgia

作　　者：高飞[1] 贾会宾[2] 冯艺[1] 

机构地区：[1]北京大学人民医院,北京100044 [2]东南大学学习科学研究中心

出　　处：《中国地方病防治》2016年第11期1219-1220,共2页Chinese Journal of Control of Endemic Diseases

基　　金：国家自然科学基金;基金编号:31671141

摘　　要：目的比较观察rTMS联合口服药物治疗和单纯口服药物治疗对早期胸腹部PHN患者的短期治疗效果。方法将PHN患者分为A、B、C三组,A组给予真rTMS联合口服药物治疗,B组给予假rTMS联合口服药物治疗,C组给予单纯口服药物治疗。连续治疗和观察12周,使用简式Mc Gill疼痛问卷(SF-MPQ)评价治疗后2周、6周、12周的治疗效果。结果 A组的治疗效果显著优于B组和C组的治疗效果,而B组和C组的治疗效果无显著性差异。结论有效的rTMS治疗能够显著增强口服药物对早期胸腹部PHN的治疗效果。Objective To compare the treatment effects of r TMS combining oral drugs and oral drugs alone on patients with early PHN at chest and abdomen.Methods Patients with PHN were divided in to group A,B and C. Group A received real r TMS combining oral drugs,and Group B received sham r TMS combining oral drugs; Group C received oral drugs alone. The treatment and observation persisted 12 weeks,the short- form Mc Gill pain questionnaire( SF- MPQ) was used to assess the treatment effects at 2,6 and 12 weeks after treatment. Results The treatment effect of Group A was significantly better than that of group B and C,while the treatment effect was not significantly different between group B and C. Conclusion Effective r TMS can enhance the treatment effect of oral drugs alone on patients with early PHN at chest and abdomen.

关 键 词：带状疱疹后神经痛 重复经颅磁刺激 McGill疼痛问卷 

分 类 号：R752[医药卫生—皮肤病学与性病学]