QAS及X-strain技术评价2型糖尿病患者股总动脉弹性  

Evaluation on elasticity of femoral artery with QAS and X-strain technique in patients with type 2 diabetes

作　　者：高岩[1] 侯利芳[1] 邢雨薇[1] 

机构地区：[1]哈尔滨医科大学附属第一医院体检中心,黑龙江哈尔滨150001

出　　处：《哈尔滨医科大学学报》2016年第6期536-539,544,共5页Journal of Harbin Medical University

摘　　要：目的应用定量动脉硬度检测(quantitative arterial stiffness,QAS)技术及应变和应变率成像(X-strain)技术检测2型糖尿病(type 2 diabetes,T2DM)患者股总动脉弹性功能。方法根据病程将T2DM患者分为T2DM1组(病程<5年,46例)和T2DM2组(病程≥5年,59例),另选取54名健康志愿者作为对照组。采用二维超声、QAS技术和X-strain技术检测股总动脉参数,比较各组间参数差异并分析各参数间的相关性。结果 T2DM1组的顺应性系数CC、弹性系数β、脉搏波速度PWV较对照组比较,差异有统计学意义(P<0.05),T2DM2组的α、β、PWV值高于对照组及T2DM1组,差异有统计学意义(P<0.05),3组间最大圆周应变(Cs)及圆周应变率(Csr)比较差异均有统计学意义(P<0.05),股总动脉内-中膜厚度(IMT)与QAS参数、X-strain参数之间具有显著相关性。结论采用血管硬度检测及应变和应变率成像技术能早期发现2型糖尿病患者股总动脉弹性功能减低,为临床预防糖尿病足及心血管并发症提供依据。Objective To evaluate quantitative arterial stiffness （QAS） and strain and X-strain technique on femoral arterial elasticity in patients with type 2 diabetes （T2DM）. Methods According to the course, T2DM patients were divided into T2DM1 group （duration 〈 5 years, 46 cases） and T2DM2 group （durations〉5 years, 59 cases） , and the other 54 healthy volunteers were selected as control group. Two-dimensional ultrasound, QAS and X-strain were used to detect femoral artery parameters, and parameter differences and the correlation between groups were compared and analyzed. Results Compliance coefficient （CC）, elasticity coefficient β and pulse wave velocity （PWV） of T2DM1 group, were statistically significant compared with the control group. Elasticity coefficient α, β, PWV of T2DM2 group significantly increased compared with control group and T2DM1 group （P 〈0. 05 ）, with statistical significance. The maximum value of circumferential strain （Cs） and circumferential strain rate （Csr） were significantly different among three groups （P 〈 0. 05 ）. Femoral artery IMT, QAS parame ters and X-strainparameters were significantlyeorrelated to each other. Conclusion Early de- tection of femoral artery elasticity reduction by QAS and X-strain in patients with type 2 diabe tes , provide the basis for clinical prevention of diabetic foot and cardiovascular complications.

关 键 词：2型糖尿病 股总动脉 应变 超声检查 

分 类 号：R445[医药卫生—影像医学与核医学]