低沸点溶剂中果糖制备呋喃衍生物的研究进展  

Progress in conversion of fructose into furan derivatives in low boiling point solvents

作　　者：高志谨[1,2] 李永祥[1] 胡耀平[2] GAO Zhijin LI Yongxiang HU Yaoping(School of Chemical and Environmental Engineering, North University of China, Taiyuan 030051, Shanxi, China Ningbo Institute of Industrial Technology, Chinese Academy of Sciences, Ningbo 315201, Zhejiang, China)

机构地区：[1]中北大学化工与环境学院,山西太原030051 [2]中国科学院宁波材料技术与工程研究所,浙江宁波315201

出　　处：《化工进展》2017年第3期1052-1058,共7页Chemical Industry and Engineering Progress

基　　金：中国博士后科学基金面上项目(2016M592026)

摘　　要：从生物质出发可以制备一系列的呋喃衍生物,包括5-羟甲基糠醛(5-HMF)、甲氧基甲基糠醛(MMF)、乙氧基甲基糠醛(EMF)。5-HMF是一种重要的平台化合物,以它为原料可以制备医药中间体、农药和塑料单体,MMF可以用作油品添加剂,EMF有望成为一种高能量密度的生物燃料而备受关注。本文介绍了近年来在低沸点溶剂中以果糖为原料制备5-HMF、MMF和EMF的研究进展。低沸点溶剂体系的优点是能在较低温度下通过减压蒸馏的方式挥发溶剂,实现产物与溶剂的低能耗简便分离,降低产物的分离和纯化成本,推动其大规模工业化生产。本文所述溶剂的沸点均小于100℃,不仅可作反应溶剂、萃取剂使用,还是制备MMF和EMF的反应物之一。最后,提出了在低沸点溶剂中由果糖制备呋喃衍生物所面临的挑战及解决策略,并对未来的发展方向进行了总结和展望。Biomass,a renewable energy source,can be employed to produce a series of furan derivatives, including 5-hydroxymethylfurfural（ 5-HMF）, methoxymethylfurfural（ MMF）, and ethoxymethylfurfural（EMF）. Among those chemicals,5-HMF is a promising bio-based building block that has been widely used to synthesize pharmaceutical intermediates,pesticide and plastic for pharmaceutical and chemical industries. MMF and EMF have attracted intensive attentions as a potential biofuel additive and biofuel,respectively. This review discusses the progresses in 5-HMF,MMF and EMF productions from fructose as low boiling point solvents. This process takes the advantage of facile and energy-efficient product separation via vacuum distillation to reduce the capital cost. Some solvents with boiling points below 100℃ can be used to extract 5-HMF from biphasic reaction system and serve as the reactant for MMF and EMF synthesis. The challenges and issues for producing furan derivatives are discussed and several possible strategies are proposed to solve the present problems.

关 键 词：低沸点溶剂 果糖 5-羟甲基糠醛 甲氧基甲基糠醛 乙氧基甲基糠醛 

分 类 号：O643.3[理学—物理化学]