益生菌治疗贮袋炎的研究进展  

The current place of probiotics in the treatment of pouchitis

作　　者：高森阳 刘刚[1] 

机构地区：[1]天津医科大学总医院普外科,300052

出　　处：《中华结直肠疾病电子杂志》2017年第1期60-63,共4页Chinese Journal of Colorectal Diseases(Electronic Edition)

基　　金：黎介寿院士肠道屏障研究专项基金(No.LJS_201008)

摘　　要：贮袋炎是中重度溃疡性结肠炎患者全结直肠切除回肠贮袋肛管吻合术后的常见并发症,临床表现为便次增多、便血、腹痛、发热等,目前其病因及发病机制尚未明确,但大多数学者认为贮袋菌群的改变(失调)导致了免疫激活和炎症的发生。因此,针对其菌群改变应用益生菌治疗贮袋炎成为国内外学者日益关注的课题,本文就贮袋炎的发病机制及益生菌治疗贮袋炎的现状做如下综述。Pouchitis is the common complication of modest to severe ulcerative colitis patients after ileal pouch-anal anastomosis and mainfest itself with increased stool frequency, rectal bleeding, abdominal cramping and fever. The pathogenesis of pouchitis remains incompletely elucidate, however, most researchers believe that the change of the pouch flora（disorder） would lead to the immune activation and inflammation. Therefore probiotics treatment in pouchitis against in the flora disorder is concerned by many researchers both at home and board. The pathogenesis of pouchitis and probiotics treatment was as follows.

关 键 词：消化系统 治疗 贮袋炎 全结直肠切除回肠贮袋肛管吻合术 益生菌 

分 类 号：R656.9[医药卫生—外科学]