单L-苯丙氨酸衍生物对乙醇/水混合溶剂的凝胶化研究  

GELATION OF ETHANOL/WATER MIXTURES FORMED BY SINGLE L-PHENYLALANINE-BASED MOLECULE

作　　者：冯桂龙[1,2] 钟路平[1,2] 刘小兵[1,2] 李巍 

机构地区：[1]井冈山大学化学化工学院,江西吉安3430092 [2]井冈山大学应用化学研究所,江西吉安343009 [3]襄阳岩翔化工有限公司,湖北襄阳441002

出　　处：《井冈山大学学报（自然科学版）》2017年第1期29-33,共5页Journal of Jinggangshan University (Natural Science)

基　　金：江西省教育厅科技计划项目(GJJ12473);湖北省襄阳市研究与开发项目(襄科计【2015】4号)

摘　　要：考察了单L-苯丙氨酸衍生物——L-3-[(3-硬脂胺酰基)-3-苯基-丙酰基]丁酸(SPAB)在乙醇/水混合溶剂中的凝胶行为,结果表明SPAB在乙醇/水的体积比从9:1到2:3的乙醇/水混合溶剂中能形成稳定的、热可逆的超分子凝胶。而在乙醇/水(V/V=1)溶液中的最低凝胶化浓度(MGC)低至1.2 mg/m L。凝胶的相转变温度(TGS)随凝胶因子浓度增加而升高。扫描电镜(SEM)观察到SPAB在乙醇/水混合溶剂中形成了相互交联的带状纤维聚集体。红外光谱(FTIR)结果表明SPAB分子中酰胺基团间的氢键、烷基的疏水作用以及水与SPAB分子中的羧基间的氢键是分子自组装的主要驱动力。The assembly behavior of the prepared gelator,single L-phenylalanine-based molecules 3-{[2-（stearoylamino）-3-phenyl-propanoyl] amino} butyrate（SPAB）,in ethanol/water mixed solvents was investigated in detail.The results indicated that a stable and themoreversible supramolecular gel was obtained in ethanol/water mixtures with volume ratio between 9：1 and 2：3 when cooled to the room temperature.The minimum gelation concentration（MGC） of SPAB in ethanol/water（V/V=1） mixtures was 1.2 mg/m L and the gel-to-solution phase-transition temperatures（TGS） of gel increased with the enhancing of gelator concentration.The gels were characterized by FTIR and scanning electron microscope（SEM）.The result of SEM shows that the aggregates of SPAB exhibit an interconnected network of intertwined ribbonlike.FTIR measurement suggested that the intermolecular hydrogen bonding between the amide groups,the intermolecular hydrogen bonding between the water and carboxyl group of SPAB,and the hydrophobic interaction of the alkyl chains were the main driving force for the self-assembly of the SPAB.

关 键 词：凝胶因子 超分子凝胶 L-苯丙氨酸衍生物 自组装 

分 类 号：O621.736[理学—有机化学]