舒心安神膏澄清工艺研究  

Studies on the Clarification Process of Shuxin Anshen Paste

作　　者：王家员[1] 樊建霜[1] 

机构地区：[1]浙江省温州市中医院药剂科,温州325000

出　　处：《海峡药学》2017年第2期28-30,共3页Strait Pharmaceutical Journal

基　　金：温州市医药卫生科研项目(2014ZB019)

摘　　要：目的考察壳聚糖絮凝工艺用于舒心安神膏的澄清效果以及替代水提自然沉降去杂法的可行性。方法采用正交试验法考察药液浓度、药液pH值、壳聚糖加入量三个因素对絮凝效果的影响;并比较壳聚糖絮凝工艺与水提自然沉降去杂法对阿魏酸含量和干燥得率的影响。结果药液浓度对絮凝效果有显著性影响;壳聚糖絮凝工艺阿魏酸保留率较高,干燥得率较低。结论壳聚糖絮凝工艺完全可以替代水提自然沉降去杂工艺用于舒心安神膏的澄清,并具有明显优势。OBJECTIVE To investigate the clarification effect of chitosan flocculation process in Shuxin Anshen paste and the feasibility to replace the water extraction natural precipitation method.METHODS The effects of the concentration of solution,pH and the amount of chitosan on the flocculation efficiency were investigated by orthogonal test.Chitosan flocculation process and water extraction natural precipitation method were compared with effectiveness of content of ferulic acid and drying rate.RESULTS The concentration of the solution had a significant effect on the flocculation effect.The clarifying technology of chitosan flocculation process was effective with higher retention rate of ferulic acid and lower drying rate.CONCLUSION Water extraction natural precipitation method can completely be replaced by chitosan flocculation process for clarification of Shuxin Anshen paste and also chitosan flocculation process has obvious advantages.

关 键 词：壳聚糖絮凝法 澄清 水提自然沉降去杂法 阿魏酸 膏方 中药制药工艺 

分 类 号：R94[医药卫生—药剂学]