3D-ASL在短暂性脑缺血发作中的诊断价值  

The advantage of 3D arterial spin labeling in the diagnosis of transient ischemic attack

作　　者：纪宇[1,2] 邵广瑞[2] 马帅[2] 陈佩佩[2] 

机构地区：[1]山东大学,山东济南250012 [2]山东大学第二医院影像科,山东济南250033

出　　处：《实用放射学杂志》2017年第3期361-364,共4页Journal of Practical Radiology

摘　　要：目的 探讨MR三维动脉自旋标记（3 D-ASL）灌注成像在短暂性脑缺血发作（TIA）中的诊断价值.方法 对78例临床诊断为TIA的患者行MR常规扫描[（T1WI、T2WI、T2-FLAIR、扩散加权成像（DWI）]、磁共振血管成像（MRA）和3D-ASL扫描.根据扫描结果进行χ2检验并分析.结果 78例患者中,常规扫描显示信号异常0例（0%）;MRA显示血管异常41例（52.6%）;3 D-ASL显示灌注异常47例（60.2%）;两者联合应用显示异常患者60例（76.9%）,其中MRA阳性＋ASL阳性29例;MRA阳性＋ASL阴性12例;MRA阴性＋ASL阳性19例;MRA阴性＋ASL阴性18例.结论 3 D-ASL技术在TIA的诊断上优于MR常规序列,且方便易行,应该作为TIA诊断的常规扫描序列.3 D-ASL、MRA、DWI 3种检查方法各具优缺点,联合应用可以提高TIA的诊断准确率.Objective To explore the value of magnetic resonance perfusion imaging of 3D arterial spin labeling（3D-ASL）in the diagnosis of transient ischemic attack（TIA）.Methods 78 of patients were diagnosed TIA on MR routine scan [T1 WI,T2 WI,T2-FLAIR,diffusion weighted imaging（DWI）],magnetic resonance angiography（MRA）and 3D arterial spin labeling（3D-ASL）.The re-sult were analyzed by Chi-square test.Results In 78 patients,the abnormal routine scan was 0 case（0%）;abnormal MRA 41 cases （52.6%）;abnormal 3D-ASL 47 cases（60.2%）;combination with each other were 60 cases（76.9%）.29 cases with artery stenosis and abnormal ASL,12 case with artery stenosis and normal ASL,19 cases with normal vascular and abnormal ASL,18 cases with normal vascular and normal ASL.Conclusion 3D-ASL is better than routine magnetic resonance sequences in the diagnosis of TIA,which is convenient and should be a routine scanning sequence of TIA.3D-ASL,MRA and DWI have their own advantages and disadvantages, combination use can improve the diagnosis accuracy of TIA.

关 键 词：磁共振成像 三维动脉自旋标记 短暂性脑缺血发作 脑血流灌注 

分 类 号：R445.2[医药卫生—影像医学与核医学] R743.31[医药卫生—诊断学]