2009-2015年广州口岸输入性登革热的流行病学分析  

Epidemiological analysis of imported dengue fever cases in Guangzhou from 2009 to 2015

作　　者：师永霞[1] 黄鹂[2] 廖芸 袁帅[1] 郑夔[1] 李淑芬[1] 范秀莹 李小波[1] 黄吉城[1] 

机构地区：[1]广东出入境检验检疫局检验检疫技术中心,广东广州510700 [2]广东出入境检验检疫局,广东广州510623 [3]江西国际旅行卫生保健中心,江西南昌330038

出　　处：《现代预防医学》2017年第6期965-967,共3页Modern Preventive Medicine

基　　金：国家检验检疫局科技计划项目(2011IK128);广东检验检疫局科技计划项目(No.2012GDK51)

摘　　要：目的分析广州口岸近年输入性登革热病例的流行病学情况,为国内登革热疫情的溯源和制定有效的预防控制措施提供依据。方法对2009-2015年经广州口岸入境、疑似登革热病例进行流行病学调查和登革病毒的实验室核酸检测,用描述性流行病学方法分析其流行特征和流行因素。结果 2009-2015年,使用实时荧光RT-PCR共检出输入性登革热病例152例,近3年输入病例逐步升高。89.5%病例来自亚洲,其中东南亚占87.5%,主要来源于泰国、越南、马来西亚、印度尼西亚、缅甸和新加坡等地。输入性登革热病例主要集中在21~40岁,男性占77%。全年均有输入性病例报告,其中第三季度和第四季度是高峰期,10月份输入性病例最多。结论东南亚地区的入境人员已成为广东省输入性登革热病例的重点人群。广东口岸地区面临输入性登革热的威胁,出入境检验检疫机构应及时掌握国内外疫情信息,加强口岸检疫查验、疾病监测,一旦发现疫情,及时采取有效的控制措施,防止输入性登革热造成本地疫情的爆发。Objective The aim of this study was to analyze epidemiological information of imported dengue fever cases in Guangzhou during recent years, and provide evidence for tracing the domestic dengue fever outbreak and making effective prevention and control measures. Methods From 2009 to 2015, suspected dengue fever cases to entry at Guangzhou port were subjected to epidemiologieal survey and the nucleic acid of dengue virus was detected in the lab. The epidemiological characteristic and factors were analyzed using descriptive epidemiological methods. Results A total of 152 imported dengue cases were confirmed by real time fluorescence RT-PCR from 2009 to 2015, with gradually increasing trend during recent three years. 89% cases were from Asia, with those from southeast Asia accounted for 87.5%. Most of dengue fever cases were from Thailand, Vietnam, Malaysia, Indonesia, Myanmar and Singapore. They were mainly between 21 and 40 years old and men accounted for 77%. Imported cases were reported every month with the largest number of imported cases in October, wherein the third quarter and the fourth quarter were the peak period. Conclusion Southeast Asian countries were the most important sources of dengue cases imported in Guangzhou. Guangdong ports were facing the threat of imported dengue fever. Inspection and quarantine authorities should grasp the domesticand international epidemiological information, and strengthen heath quarantine and disease surveillance. Once dengue fever case is detected, effective control measures should be taken to prevent spreading and causing domestic outbreak.

关 键 词：输入性登革热 东南亚 实时荧光RT-PCR 流行病学分析 

分 类 号：R181.22[医药卫生—流行病学]