双相心境障碍抑郁发作患病严重程度的影响因素分析  

Analysis of related factors influencing depression severity of bipolar disorder

作　　者：庚天琦 安妮[1] 王喜今 江海冰 庞厚远 张旸[1] 

机构地区：[1]哈尔滨医科大学公共卫生学院,黑龙江哈尔滨150000 [2]哈尔滨市第一专科医院,黑龙江哈尔滨150000 [3]哈尔滨市中医医院,黑龙江哈尔滨150000

出　　处：《现代预防医学》2017年第6期1145-1148,共4页Modern Preventive Medicine

基　　金：哈尔滨市科技创新人才基金课题(2014RFXXJ106)

摘　　要：目的研究影响双相心境障碍疾病抑郁发作期严重程度的危险因素,为该病的有效预防提供理论依据。方法收集2010-2015年某市精神专科医院的双相心境障碍抑郁发作住院466名患者的病例信息,根据汉密尔顿抑郁量表将患者分为轻、中、重度,并选出年龄、性别、居住地、出生季节、遗传史等15个可能危险因素,进行单因素和多因素条件Logistic回归分析。结果 Logistic回归分析筛选出7个影响双相心境障碍疾病抑郁发作严重程度的危险因素,即出生季节(冬季OR=3.091、秋季OR=2.363)、高学历(OR=1.414)、婚姻离异(OR=3.132)、长期居住农村(OR=0.587)、排行老大(OR=1.461)、性格内向(OR=1.705)、家族遗传史(OR=2.101)。结论双相心境障碍抑郁发作严重程度受多种因素的影响。Objective This work was to study the related factors of depression severity of bipolar disorder and to provide the theoretical basis for the effective prevention of the disease. Methods Data of 466 depression patients of bipolar mood disorder were collected in the mental hospital from 2010 to 2015. Based on the Hamilton depression rating scale, these patients were divided into three groupsof light, medium and heavy levels. Fifteen factors including age, sex, habitation, season of birth, family heredity, etc, were analyzed as related factors using Logistic regression analysis. Results Finally seven related factors of bipolar mood disorder were identified, including the birth season （OR =3.091 （winter）, OR =2.363 （autumn））, highly educational level （OR = 1.414）, divorce （OR =3.132）, long-term living in the rural areas （OR =0.587）, leading rank （OR = 1.461） and introversion （OR=1.705）, family genetic history （OR=2.101）. Conclusion The severity of depressive episode of bipolar disorder was influenced by multiple factors.

关 键 词：双相心境障碍 病例回顾分析 危险因素 LOGISTIC回归 

分 类 号：R395.2[哲学宗教—心理学]