负压封闭吸引技术治疗慢性溃疡及其对周围组织代谢的影响  

Vacuum sealing drainage for treatment of chronic wound and metabolism of surrounding tissue

作　　者：陈元庄[1] 罗裕强 胡女元[1] 黄远翘[1] 邹承浩[1] 

机构地区：[1]广东省江门市中心医院四肢关节骨科,广东江门529030

出　　处：《中国现代医学杂志》2017年第5期117-120,共4页China Journal of Modern Medicine

基　　金：2016年度江门市第一批科技计划项目(No:201607)

摘　　要：目的评价负压封闭引流(VSD)技术在肢体皮肤慢性溃疡中的疗效及其对周围组织代谢的影响。方法选取2014年6月2016年6月对84例皮肤慢性溃疡患者的创面分别以VSD技术(实验组62例)及常规清创、换药方法(对照组22例)进行处理最后采用皮瓣移植修复,比较两种方法的疗效及周围组织经皮氧分压。结果实验组中平均手术清创次数为(1.9±0.4)次,平均住院日为(24±4)d,并发症发生率3.2%,皮瓣修复手术当天TcPO_2平均值(47.5±7.2)mmHg。对照组中平均手术清创次数为(3.1±0.9)次,平均住院日为(38±7)d,并发症发生率为40.9%,皮瓣修复手术当天TcPO_2平均值(35.3±6.8)mmHg。所有指标两组间差异有统计学意义(P<0.05)。结论VSD技术联合皮瓣修复可改善慢性溃疡创面周围组织的氧分压,降低术后并发症发生率,且手术次数及住院日较常规换药处理明显减少。Objective To investigate the clinical efficacy of vacuum sealing drainage （VSD） for the treatment of chronic wound and the metabolism of surrounding tissue. Methods From June 2014 to June 2016, VSD （treatment group, 62 cases） or conventional dressing （control group, 22 cases） combined with dermatoplasty was used to treat 84 patients with chronic wound. The efficacy and transcutaneous oxygen pressure of Day-admission and Day-operation were evaluated. Results The time of debridement, average hospital stay, complication rate and TcPO2-operation of treatment group respectively were （1.9 ± 0.4） times, （24 ± 4） days, 3.2% and （47.5 ± 7.2） mmHg, while concerning control group were （3.1 ± 0.9） times, （38 ± 7） days, 40.9% and （35.3 ± 6.8） mmHg. All evaluated indexes were significantly different between treatment group and control group （P〈0.05）. Conclusions VSD combined with dermatoplasty used for the treatment of chronic wound may manage to provide a hyperoxic environment of surrounding tissue and decrease the time of debridement, complication rate and hospital stay.

关 键 词：负压封闭引流 慢性溃疡 经皮氧分压 

分 类 号：R722.142[医药卫生—儿科]