内蒙古乌海市成人超重肥胖和甜饮料摄入对血尿酸的影响  

The effects of overweight,obesity and sugar-sweetened beverage consumption on serum uric acid in adult residents of Wuhai,Inner Mongolian

作　　者：刘琰[1] 宋菲[1] 伍思佳 焦玮玉 刘爱萍[1] 王培玉[1] 王东平[2] 王浩杰[2] 宋阳[3] 

机构地区：[1]北京大学公共卫生学院社会医学与健康教育学系,北京100191 [2]乌海市疾病预防控制中心中心办公室,内蒙古乌海016000 [3]乌海市疾病预防控制中心慢性病防制科,内蒙古乌海016000

出　　处：《中华疾病控制杂志》2017年第3期228-232,共5页Chinese Journal of Disease Control & Prevention

摘　　要：目的探索内蒙古乌海市成人超重肥胖和甜饮料(sugar-sweetened beverage,SSB)摄入与血尿酸(serum uric acid,SUA)的关系。方法采用多阶段分层整群抽样,对内蒙古乌海市5 995名居民展开横断面调查。采用多因素Logistic回归进行分析。结果男女超重、肥胖组SUA水平及高尿酸血症(hyperuricemia,HUA)检出率均高于正常组(均有P<0.05);男性SUA水平随SSB摄入量的增加依次增加(F=3.426,P=0.033,P_(trend)=0.010),SSB摄入频率较高者的SUA水平也较高(t=-2.204,P=0.028);女性SSB摄入量及摄入频率较高者,SUA水平反而较低(均有P<0.05)。多因素Logistic回归分析结果显示,男女超重、肥胖者HUA患病风险增加。超重肥胖与SSB摄入量对HUA检出率存在交互作用(均有P_(interaction)<0.05)。结论超重或肥胖是HUA的独立危险因素,摄入SSB会增加男性SUA水平。超重或肥胖同时增加SSB摄入会提高HUA患病风险。Objective To investigate the effects of overweight, obesity and sugar-sweetened beverage（SSB）consumption on serum uric acid （SUA）in adult residents of Wuhai, Inner Mongolian. Methods A total of 5 995 subjects were enrolled in this study using multiple stage stratified cluster sampling. Multivariate logistic regression analysis was conducted for data analysis. Results The SUA levels and detection rates of hyperuricemia （HUA） in overweight group and obesity group were significantly higher than those in normal weight group（ all P 〈 0. 05 ）both in males and females. Higher SSB intake and intake frequency increased the SUA levels in males （ all P 〈 0. 05 ） and the former with a linear trend （ Ptrend = 0. 010） ; On the contrary, higher SSB intake and intake frequency decreased the SUA levels in females （all P 〈 0. 05 ）. Multiple logistic regression analysis showed that overweight and obesity enhanced the risk of HUA both in males and females. There was an interaction between overweight/obesity and SSB intake on SUA level （ all Pinteraction 〈 0. 05 ） . Conclu- Overweight or obesity are the independent risk factors of HUA. SSB intake could increase SUA level in males. Overweight or obesity with higher beverage intake couht significantly enhance the risk of HUA.

关 键 词：高尿酸血症 超重 肥胖症 饮料 

分 类 号：R589.25[医药卫生—内分泌] R155.59[医药卫生—内科学]