伴放线放线杆菌性败血症一例  

Report of one case with Aggregatibacter actinomycetemcomitans septicemia

作　　者：金柯 刘根焰 李军[1] 翁亚丽 

机构地区：[1]南京医科大学第一附属医院感染病科,南京市210029 [2]南京医科大学第一附属医院检验科,南京市210029

出　　处：《中华实验和临床感染病杂志（电子版）》2017年第1期92-94,共3页Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)

基　　金：国家重大科技专项(No.2013ZX10002005-002-005;2013ZX10004905);江苏省医学创新团队与领军人才项目(No.LJ201121)

摘　　要：目的探讨伴放线放线杆菌性败血症的临床特征及抗菌药物的选用。方法对本院收治的1例伴放线放线杆菌性败血症患者的临床资料、诊治经过及预后进行回顾性分析。结果本例伴放线放线杆菌性败血症患者为56岁男性,长期于地下停车场工作且以夜间为主,主要临床表现为低热、消瘦。血培养至第8天见细菌生长,第19天时鉴定为伴放线放线杆菌感染。给予莫西沙星抗感染治疗后,患者体温恢复并持续正常,复查炎性标志物等基本正常,复查血培养未见细菌生长。结论对于长程发热患者需尽早进行血培养,且当怀疑为苛养菌所致血流感染时血培养观察时间应延长;抗伴放线放线杆菌治疗可选择喹诺酮类药物。Objective To investigate the clinical features and antibacterials selection of Aggregatibacter actinomycetemcomitans septicemia. Methods The clinical manifestations, treatment and prognosis of one patient with Aggregatibacter actinomycetemcornitans septicemia in our hospital in 2015 was analyzed, retrospectively. Results The case was a 56 years old man who worked at underground parking garage nightly. The main clinical manifestations were low-grade fever and weight loss. Bacterial growth appeared in blood culture at the eighth day after sampling, and identified as Aggregatibacter actinomycetemcomitans at the nineteenth day. After the treatment with moxifloxacin, the patient recovered, while the inflammatory markers returned to be nearly normal and no bacterium grew in the reexamination of blood culture. Conclusions Blood culture should be done as soon as possible to the patients with prolonged fever and the observation period for blood culture should be extended when a fastidious bacterium bloodstream infection is suspected. Moxifloxacin is appropriate for the treatment of Aggregatibacter actinomycetemcomitans infection.

关 键 词：伴放线放线杆菌 败血症 

分 类 号：R515.3[医药卫生—内科学]