唑来膦酸针与伊班膦酸钠针治疗骨肿瘤的临床对照研究  

A Clinical Comparison of Zoledronic Acid and Ibandronate in the Treatment of Bone Tumors

作　　者：李林勍[1] 罗毅[1] 刘剑帆[1] 徐学政[1] 李先安[1] 黄钢[1] LI Linqing LUO Yi LIU Jianfan XU Xuezheng LI Xian＇an HUANG Gang(Bone and Soft Tissue Department, The Affiliated Cancer Hospital of Xiangya School of Medicine in Central South University, Changsha Hu ＇nan 410013. China)

机构地区：[1]湖南省长沙市中南大学湘雅医学院附属肿瘤医院骨软组织科,湖南长沙410013

出　　处：《中国卫生标准管理》2017年第4期91-93,共3页China Health Standard Management

摘　　要：目的探讨唑来膦酸针与伊班膦酸钠针治疗骨肿瘤的临床效果。方法整取抽样我院2014年6月—2015年6月就诊的骨肿瘤患者56例,分为两组,对照组28例,给予唑来膦酸针治疗,观察组28例,给予伊班膦酸钠针治疗,比较两组疼痛缓解情况,及不良反应发生率。结果观察组疼痛缓解率和生活质量改善率均高于对照组(P<0.05),不良反应发生率及治疗费用低于对照组(P<0.05)。结论对骨肿瘤采取伊班膦酸钠针治疗的疗效优于唑来膦酸针治疗,且毒副作用少,费用低。Objective To investigate the clinical effect of zoledronic acid and ibandronate in the treatment of bone tumors.Methods 56 patients with bone tumor treated in our hospital from June 2014 to June 2015,were divided into two groups,28 patients in the control group,28 patients were treated with zoledronic acid for observation.The pain relief was compared between the two groups,and the incidence of adverse reactions was compared.Results The rate of improvement of pain and quality of life in the observation group was higher than that of the control group（P〈0.05）.The incidence of adverse reaction and the cost of treatment were lower than those of the control group（P〈0.05）.Conclusion The therapeutic effect of ibandronate on bone tumor is superior to that of zoledronic acid in treatment of bone neoplasms with less side effects and low cost.

关 键 词：骨肿瘤 唑来膦酸针 伊班膦酸钠针 

分 类 号：R977[医药卫生—药品]