福尔利与丙泊酚用于腹腔镜胆囊切除术临床观察  

Clinical observation of forli and propofol in laparoscopic cholecystectomy

作　　者：孔雅君 

机构地区：[1]凤翔县医院,陕西宝鸡721400

出　　处：《临床医学研究与实践》2017年第9期39-40,共2页Clinical Research and Practice

摘　　要：目的观察福尔利在腹腔镜胆囊切除术的临床应用,并比较其与丙泊酚的优缺点。方法选择2015年1月至2016年6月我院行腹腔镜胆囊切除术的患者200例作为研究对象,随机分为福尔利组和丙泊酚组,每组100例,分别给予福尔利和丙泊酚进行麻醉,监测并记录两组患者给药、插管、手术开始前后的HR、MAP及Sp O2的变化情况,苏醒时间,用药后并发症发生情况。结果给药,插管,手术开始前、后同组患者的HR、MAP、Sp O2组内比较无明显差异(P>0.05)。插管,手术开始前、后,福尔利组患者的HR、MAP显著优于丙泊酚组(P<0.05)。两组的苏醒时间比较无显著差异(t=1.3696,P>0.05)。福尔利组注射痛发生率明显低于丙泊酚组,但肌肉阵挛、恶心呕吐及总不良反应总发生率均显著高于丙泊酚组(P<0.01)。结论福尔利和丙泊酚均能安全地用于腹腔镜胆囊切除术的麻醉,与丙泊酚相比较,福尔利对血流动力学的影响更小,注射痛少,患者苏醒快,但肌阵挛和呕吐发生率较高,临床需根据患者的实际情况选择合适的麻醉药。Objective To investigate the clinical application of forli in laparoscopic cholecystectomy, and compare the advantages and disadvantages with propofol. Methods Two hundred cases of patients with laparoscopic cholecystectomy in our hospital were selected from 2015 January to June 2016 and randomly divided into forli group and propofol group, with 100 cases in each group and treated with forli, propofol respectively. The HR, MAP and SpO2 before and after drug administration, tracheal intubation, surgery, the awakening time and complications were determined and recorded between the two groups. Results There were no significant differences of the HR, MAP and SpO2 before and after drug administration, tracheal intubation, surgery of the intra-group comparison of the two groups （P〉0.05）. The HR and MAP of the forli group before and after the tracheal intubation, surgery were better than those of the propofol group （P〈0.05）. There were no significant differences of the awakening time between the groups （t=1.3696, P〉0.05）. The injection pain rate of the forli group was lower than that of the propofol group, and the incidence of muscle clonus, nausea and vomiting and the total incidence of adverse reactions of the fodi group were significantly higher than those of the propofol group （P〈0.01）. Conclusion Foley and propofol are safe for anesthesia in laparoscopic cholecystectomy. But compared with propofol, foley has less effect on hemodynamics, with less injection pain, patients can wake up quickly, and it has a higher incidence of muscle clonus, nausea and vomiting, clinical need to choose the appropriate anesthetic according to the actual situation of patients.

关 键 词：福尔利 丙泊酚 腹腔镜胆囊切除术 

分 类 号：R614[医药卫生—麻醉学]