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机构地区:[1]北京航天总医院妇产科,北京100076 [2]北京航天总医院医院感染管理处,北京100076
出 处:《中国实验诊断学》2017年第3期451-454,共4页Chinese Journal of Laboratory Diagnosis
摘 要:目的探讨产褥期下肢深静脉血栓的发病情况及防治措施。方法回顾性分析2010年1月至2014年12月北京航天总医院住院分娩出现产褥期急性下肢深静脉血栓17例患者,确诊后给予抗凝、溶栓及手术取栓等综合性治疗,观察分析产妇治疗前后临床表现及凝血功能变化。结果产褥期急性下肢深静脉血栓早期发现经治疗可取得满意疗效,17例患者采用低分子肝素抗凝、溶栓及手术等综合治疗后,疗效满意,4例出现肺栓塞,经抢救均成功,治疗后血浆纤维蛋白原和D-二聚体明显降低,P<0.05,差异有统计学意义,治疗前后PT、APTT变化不明显,P>0.05,差异无统计学意义。结论产褥期下肢静脉血栓多发病于产褥早期,及时发现,抗凝及溶栓治疗安全有效。Objective To investigate the incidence and prevention of postpartum lower extremity deep vein thrombosis. Methods A retrospective analysis from January 2010 to December 2014 in Beijing Aerospace General Hospital hospitalized childbirth appear puerperal acute lower extremity deep venous thrombosis in 17 patients after diagnosis,anticoagulation,thrombolysis and thrombectomy and other comprehensive treatment, to observe the changes of clinical symptoms and blood coagulation function before and after treatment were analyzed. Results The puerperal period of acute lower extremity deep venous thrombosis early found after treatment can obtain satisfactory curative effect, 17 cases were treated with low molecular heparin anticoagulation,thrombolysis therapy and surgical therapy,4 cases with pulmonary embolism,after the rescue was successful,after treatment of plasma fibrinogen and d-dimer decreased two,P〈 0.05, there were statistically significant differences before and after treatment, Pt, APTT did not change significantly, P〉0.05, the difference was not statistically significant. Conclusion Lower extremity venous thrombosis puerperium disease in early puerperium,timely,safe and effective anticoagulant and thrombolytic therapy.
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