化瘀通腑法对重度颅脑损伤患者术后脑代谢及脑灌注的影响  

Effect of Huayu Tongfu method on cerebral metabolism and cerebral perfusion after severe craniocerebral injury

作　　者：谢有鑫 吴利军 

机构地区：[1]浙江省衢州市中医医院重症医学科,浙江衢州324002

出　　处：《中国现代医生》2017年第3期110-112,116,共4页China Modern Doctor

基　　金：浙江省衢州市科技局指导性科技项目(2016102)

摘　　要：目的观察化瘀通腑法对重度颅脑损伤患者术后症状、脑代谢及脑灌注的影响。方法将80例重度颅脑损伤术后患者随机分为对照组和治疗组,对照组予常规治疗,治疗组在对照组的基础上加用化瘀通腑中药,对两组患者的症状、脑代谢和脑灌注进行比较。结果与对照组比较,治疗组在用药后第2周有更低的颈内静脉-动脉乳酸差,更高的格拉斯哥昏迷指数、脑氧摄取率和脑灌注压,差异有统计学意义(P<0.05)。结论化瘀通腑法能一定程度上改善重度颅脑损伤患者术后的症状、脑代谢和脑灌注等。Objective To observe the effect of Huayu Tongfu method on postoperative symptoms, brain metabolism and cerebral perfusion in patients with severe craniocerebral injury. Methods A total of 80 cases of severe craniocerebral injury patients were randomly divided into control group and treatment group. The control group was treated with con- ventional treatment, and the treatment group was given the traditional Chinese medicine with Huayu Tongfu method on the basis of the conventional treatment in the control group. The symptoms, brain metabolism and brain perfusion be- tween the two groups were compared. Results Compared with the control group, the treatment group had lower internal jugular vein-artery lactic acid difference, and higher Glasgow coma index, cerebral oxygen uptake rate and cerebral perfusion pressure in the second week after treatment, and the difference was statistically significant（P〈0.05）. Conclu- sion Huayu Tongfu method can improve the symptoms of severe craniocerebral surgery patients, brain metabolism and brain perfusion to a certain extent.

关 键 词：化瘀通腑法 脑损伤 脑代谢 脑灌注 

分 类 号：R269[医药卫生—中西医结合]