宽体探测器全肾脏CT灌注扫描持续时间对灌注参数的影响  

Influence of Duration of Scan Acquisition on Perfusion Parameters of Whole Renal Perfusion by Wide Detector Multidetector CT

作　　者：刘静红[1] 刘爱连[1] 王逸敏[1] 方鑫[1] 刘义军[1] 刘晓峰[1] 田士峰[1] LIU Jinghong LIUAilian WANG Yimin FANG Xin LIU Yijun LIU Xiaofeng TIAN Shifeng(Department of Radiology, the First Hospital Affiliated to Dalian Medical University, Dalian 116011, China)

机构地区：[1]大连医科大学附属第一医院放射科,辽宁大连116011

出　　处：《中国医学影像学杂志》2017年第2期141-145,共5页Chinese Journal of Medical Imaging

摘　　要：目的探讨应用Revolution CT行轴位全肾脏灌注成像,扫描持续时间对灌注参数值的影响。资料与方法前瞻性研究双侧肾脏无器质性病变患者42例,按照灌注扫描持续时间将患者分为短灌注组(A组)和长灌注组(B组)。使用Revolution CT机轴扫模式进行灌注扫描,探测器宽度16 cm。A组采用管电压80 k Vp,管电流200 m A,每2 s(曝光0.5 s,间隔1.5 s)采集1次,共采集25期图像,总灌注时间50 s。B组采用管电压120 k Vp,管电流55 m A,采用间隔采集,每次采集时间均为2 s(曝光0.5 s,间隔1.5 s),最终获得23期图像,总灌注时间为594 s。使用CT Perfusion4D灌注软件包进行后处理,选择右侧肾门水平腹主动脉为输入动脉,得到灌注参数图。分别比较两组组内双侧肾脏皮髓质间各灌注参数及两组间肾脏皮髓质各灌注参数间的差异。记录CT容积剂量指数(CTDIvol)及剂量-长度乘积(DLP),计算并比较有效剂量(ED)。结果两组组内双侧肾脏各灌注参数对比差异无统计学意义(P>0.05)。两组间肾脏皮、髓质的血容量、达峰时间及表面通透性差异均有统计学意义(P<0.05)。两组间肾脏髓质的平均通过时间差异有统计学意义(P<0.05),而皮、髓质的血流量和皮质的平均通过时间差异无统计学意义(P>0.05)。A组灌注扫描、髓质期及排泄期的总ED平均为(23.10±4.39)m Sv;B组为(23.19±0.00)m Sv,差异无统计学意义(P>0.05)。结论全肾脏灌注成像中,短灌注时间与长灌注时间的灌注参数具有明显差异,因此需根据不同临床需要设计扫描时间。Purpose To explore the influence of duration of scan acquisition on perfusion parameters in whole renal perfusion with Revolution CT. Materials and Methods Fortytwo patients without pathologic changes in bilateral kidneys were divided into group A（with short perfusion time） and group B（with long perfusion time） according to the duration time of the perfusion scan. The Revolution CT axial scan mode was used for perfusion scan, and the width of detector was 16 cm. The perfusion CT series were performed in 50 seconds, each comprising 25 volumes with identical parameters（80 k Vp, 200 m A） in group A. The perfusion CT series were performed in 594 seconds, each comprising 23 volumes with identical parameters（120 k Vp, 55 m A） in group B. The source datasets were post-processed with CT Perfusion 4D software, and the perfusion parameter maps were obtained when right renal abdominal aorta was taken as entry artery. Perfusion parameters of bilateral kidneys were compared within and between group A and group B, respectively. CT dosage index of volume（CTDIvol） and dose length product（DLP） were recorded. The effective dose（ED） was calculated and compared. Results There were no statistical difference in all parameters between bilateral kidneys within each group（P〈0.05）. However, blood volume, time to peak, and permeability surface in the cortex and medulla of bilateral kidneys all showed differences between the above two groups（P〈0.05）. The mean transit time in the medulla between the two groups was different（P〈0.05）, but neither the blood flow in the medulla and cortex nor the mean transit time of the cortex had difference between the two groups（P〈0.05）. The effective radiation doses were（23.10±4.39） m Sv in group A and（23.19±0.00） m Sv in group B, respectively（without statistic difference： P〈0.05）. Conclusion CT perfusion parameters with different duration time show differences in whole renal perfusion; therefore, scanning time needs to be set according to

关 键 词：肾 体层摄影术 X线计算机 血管造影术 灌注成像 肾血流量 有效 

分 类 号：R445.3[医药卫生—影像医学与核医学]