雪里见化学成分研究  

Chemical Constituents of Arisaema rhizomatum

作　　者：何康[1] 王进喜[1] 殷海[1] 杜江[1] HE Kang WANG Jin-xi YIN Hai DU Jiang(Key Laboratory of Miao Medicine of Guiyang College of Traditional Chinese Medicine, Academician Workstation of Guiyang College of Traditional Chinese Medicine, Guiyang 550002, Chin)

机构地区：[1]贵阳中医学院苗医药重点实验室/贵阳中医学院院士工作站,贵州贵阳550002

出　　处：《中药材》2016年第10期2244-2246,共3页Journal of Chinese Medicinal Materials

基　　金：国家科技支撑项目(2012B127B06);贵州省科技厅联合基金项目(黔科合LH字[2015]7277号);贵阳中医学院院内项目(贵中医院内[2014]40号)

摘　　要：目的：研究苗药雪里见的化学成分。方法：雪里见用90%甲醇冷浸提取,经D-101大孔树脂柱用不同比例的乙醇水洗脱,对各洗脱部分采用多种柱层析技术进行分离纯化,通过波谱数据分析进行结构鉴定。结果：从雪里见中分离鉴定了8个化合物,分别为：豆甾醇（1）、雪胆甲素（2）、psiguanin A（3）、木栓酮（4）、胸苷（5）、环阿尔廷醇（6）、β-谷甾醇（7）、胡萝卜苷（8）。结论：其中,化合物2～6为首次从该属植物中分离得到,化合物2～6为首次从该植物中分离得到。Objective： To study the chemical constituents of Arisaema rhizomatum. Methods： The air-dried Arisaema rhizomatum was extracted with 90% Me OH by cold leaching. The extract was suspended in H2 O and applied to macroporous resin D101 with Et OH and H2 O to afford polar portions. The compounds were isolated and purified by column chromatography,and identified based on spectral analysis from these portions. Results： Eight compounds were isolated from Arisaema rhizomatum,and characterized as stigmasterol（ 1）,hemslecin A（ 2）,psiguanin A（ 3）,friedelin（ 4）,thymidine（ 5）,cycloartenol（ 6）,β-sitosterol（ 7）,daucosterol（ 8）. Conclusion： Compounds 2 ~ 6 are isolated from this genus for the first time,compuonds 2 ~ 6 are isolated from this plant for the first time.

关 键 词：雪里见 化学成分 三萜 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]