PET-CT、SPECT及SPECT-CT受检者辐射水平及其生物效应研究进展  被引量:12

Research Progress on radiation levels and biological effects of PET-CT, SPECT and SPECT-CT subjects

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作  者:吴一田 耿建华[1] 

机构地区:[1]北京协和医学院,中国医学科学院肿瘤医院核医学科、PET-CT中心,北京100021

出  处:《中国医学装备》2017年第3期141-146,共6页China Medical Equipment

基  金:国际科技合作项目(2009DFA32960)“PET-CT脑分子影像研究与应用平台及针灸中枢机理探索”;中国癌症基金会北京希望马拉松专项(LC2013A13和LC2016A02)“PET-CT的辐射剂量和图像质量的模型研究”和“PET-CT及SPECT、SPECT-CT受检者辐射剂量的研究”

摘  要:PET-CT、SPECT及SPECT-CT检查会给受检者带来不可避免的医疗照射,这些检查所致辐射剂量的多少及其是否会给人体带来损伤成为了公众及专业人员关注的重点问题,而小剂量照射对人体的生物效应的研究目前仍存在争议。为此,对PET-CT、SPECT及SPECT-CT检查所致辐射剂量及其生物效应的研究进展进行调研综述,在达到临床需求的条件下,应尽量降低PET-CT、SPECT及SPECT-CT检查对受检者的照射剂量。但单次检查的辐射剂量不会导致确定性效应,其产生的线性无阈的随机性效应观点也遇到研究质疑。PET-CT, SPECT, and SPECT-CT examinations could lead to inevitable medical exposure for patients, and the radiation dose of this examinations and whether it was harmful to patients have attracted attention from the public and professionals. At the same time, there was still a controversy about whether the biological effect of low dose radiation was useful to human body. The research investigates and reviews the radiation dose of PET-CT, SPECT, and SPECTCT scans and their biological effects. Under achieved to the demands of clinical conditions, operators should try to reduce the radiation dose of PET-CT, SPECT, SPECT-CT scans for patients. Although PET-CT, SPECT, SPECT-CT scans deliver inevitable radiation, the dose of single examination will not lead to deterministic effect, and even the view of the random effect of linear no-threshold from these scans also have been questioned.

关 键 词:PET-CT SPECT-CT 受检者 辐射剂量 生物效应 

分 类 号:R142.4[医药卫生—公共卫生与预防医学]

 

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