桂枝茯苓胶囊联合磷霉素氨丁三醇散治疗盆腔炎并盆腔积液的临床研究  

Clinical study of Guizhi Fuling capsules combined with fosfomycin trometamol power on pelvic inflammatory disease and pelvic effusion

作　　者：江胜林[1] 吴建荷 方浴娟[1] 

机构地区：[1]浙江医院分院妇产科

出　　处：《中国生化药物杂志》2017年第3期110-112,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的 分析磷霉素氨丁三醇散联合桂枝茯苓胶囊治疗盆腔炎并盆腔积液的临床价值。方法 选取2013年2月～2016年3月浙江医院分院收治的60例盆腔炎并盆腔积液患者,按随机数字表法分为对照组与观察组,每组各30例,对照组采用磷霉素氨丁三醇散治疗,观察组在对照组基础上加用桂枝茯苓胶囊治疗,比较2组治疗效果及中医症候积分的变化,测定治疗前后2组血清C-反应蛋白（CRP）水平的变化,并作超声检查,测定治疗前后盆腔积液直径的变化。结果 观察组治疗总有效率高于对照组,差异有统计学意义（P〈0.05）;治疗前,2组各中医症候积分对比差异无统计学意义,治疗后,2组中医症候积分均降低,差异有统计学意义（P〈0.05）,观察组腰骶胀痛、腹部疼痛、带下增多、疲乏低热、腰酸积分均低于对照组,差异有统计学意义（P〈0.05）;治疗前,2组盆腔积液、CRP水平对比差异无统计学意义,治疗后,2组盆腔积液直径降低、CRP水平下调,差异有统计学意义（P〈0.05）,观察组治疗后盆腔积液直径及CRP水平均低于对照组,差异有统计学意义（P〈0.05）。结论 采用磷霉素氨丁三醇散联合桂枝茯苓胶囊治疗盆腔炎并盆腔积液患者,有其较高的临床效果,可明显减轻患者机体炎症反应,改善其中医症候积分。Objective To analyze the clinical value of Guizhi Fuling capsules combined with fosfomycin trometamol power in the treatment of pelvic inflammatory disease and pelvic effusion.Methods A total of 60 patients with pelvic inflammatory disease and pelvic effusion from February 2013 to March 2016 in our hospital were selected and divided into the control group and the observation group , 30 cases in each group.The control group were treated with fosfomycin trometamol power, and the observation group were additionally treated with Guizhi Fuling capsules.The therapeutic effects and changes of TCM syndrome scores were compared between the two groups.The levels of serum C reactive protein （ CRP ） in the two groups were determined before and after treatment and the ultrasound examination was performed and changes of pelvic effusion diameter was determined before and after treatment.Results The total effective rate of the observation group was higher than that of the control group, the difference was statistically significant （P〈0.05）.There was no significant difference in TCM syndrome scores between the two groups before treatment .After treatment, the TCM symptom scores of both groups were decreased, the difference was statistically significant （ P〈0.05 ） .The scores of lumbosacral swelling pain, abdominal pain, morbid leucorrhoea increase, fatigue, low-grade fever and soreness of waist in the observation group were lower than those in the control group, the difference was statistically significant （P〈0.05）.Before treatment, there was no statistically significant difference in pelvic effusion and CRP levels between the two groups.After treatment, the pelvic effusion diameter and CRP levels were decreased, the difference was statistically significant （P〈0.05）, and those in the observation group were lower than the control group, the difference was statistically significant （P〈0.05）. Conclusion Guizhi Fuling capsules combined with the fosfomycin trometamol power is significantly effective i

关 键 词：盆腔炎 盆腔积液 磷霉素氨丁三醇散 桂枝茯苓胶囊 联合 

分 类 号：R271.9[医药卫生—中西医结合]