变应性鼻炎皮下特异性免疫治疗研究进展  

Research progress on subcutaneous specific immunotherapy of allergic rhinitis

作　　者：裴莹莹[1] 徐博怀 胡德强[2] 张彬[2] 何勇[2] 

机构地区：[1]宁波大学,宁波在读研究生315211 [2]宁波大学附属医院耳鼻喉科,宁波315020

出　　处：《新医学》2017年第3期148-152,共5页Journal of New Medicine

基　　金：2016年宁波市医学科技计划项目;SP-A基因多肽性与特异性免疫治疗变应性鼻炎的效果关联研究(2016A13)

摘　　要：变应性鼻炎是耳鼻喉科常见病,多发病,治疗方法多样,但却难以达到临床治愈的目的。特异性免疫治疗(SIT)因其良好的安全性和有效性逐渐成为变应性鼻炎重要的治疗手段之一。随着对其作用机制的深入研究,以及新的疫苗的研发,SIT更多的用于临床变应性鼻炎的治疗。现就变应性鼻炎概况、皮下SIT机制、疗效评判、安全性及新进展作一综述。Allergic rhinitis is a common and frequently-occurring disease in the Department of Ear,Nose and Throat（ENT）.It is difficult to cure allergic rhinitis although there are a variety of therapies.Specific immunotherapy（SIT） has gradually become one of the pivotal therapies of allergic rhinitis due to high clinical efficacy and safety.Along with the deepening understanding of the mechanism underlying SIT and the development of new vaccines,SIT is likely to be more widely applied in clinical treatment of allergic rhinitis.This review summarizes the brief introduction of allergic rhinitis,the latest research progress on SIT mechanism,assessment of clinical efficacy and safety of SIT.

关 键 词：变应性鼻炎 皮下特异性免疫治疗 新进展 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]