正交设计法优选参耐颗粒的超声提取工艺  

Optimization of Extraction Technology of Shennai Granules by Orthogonal Design

作　　者：王微[1] 郑飞[1] 葛岩[1] 刘淑莹[1] 越皓[1] 

机构地区：[1]长春中医药大学药学院/吉林省人参科学研究院,吉林长春130117

出　　处：《中国医院用药评价与分析》2017年第2期167-169,172,共4页Evaluation and Analysis of Drug-use in Hospitals of China

基　　金：公益性行业(农业)科研专项(No.201302111)

摘　　要：目的:正交设计法优选参耐颗粒的超声提取工艺。方法:采用正交设计法,以黄芪甲苷和总皂苷含量为考察指标,以超声功率、料液比、提取时间、提取次数为考察因素,优选参耐颗粒的提取工艺。结果:参耐颗粒最佳提取工艺为加药材量8倍量60%乙醇,以100 W的功率超声提取3次,1次60 min。结论:该工艺简单、重复性好,可为参耐颗粒的制备提供依据。OBJECTIVE ：To optimize the extraction technology of Shennai granules by orthogonal design. METHODS ： By orthogonal design method, to set astragaloside and total saponins contents as indicators; ultrasonic power, solid-liquid rate, extraction time, extraction times were set as determination factors, and extraction technology of Shennai granules were optimized. RESULTS： The optimized extraction technology of Shennai granules were 8 times the amount of medicinal materials with 60% alcohol, 100 W power were adopted to extracted 3 times, 60 min for each. CONCLUSIONS： The technology is simple with good reproducibility, which can provide reference for the preparation of Shennai granules.

关 键 词：正交试验 黄芪甲苷 人参总皂苷 

分 类 号：R285.2[医药卫生—中药学]