六神丸配伍复合维生素B治疗白血病化疗后口腔溃疡的疗效及护理  

Efficacy and Nursing of Liushen Pills Combined with Compound Vitamin B in Treatment of Oral Ulcer after Leukemia Chemotherapy

作　　者：关玉萍[1] 秦翠[1] 宋涛[1] 魏文科[1] 黄姝[1] 

机构地区：[1]潜江市中心医院口腔科,湖北潜江433100

出　　处：《中国医院用药评价与分析》2017年第2期204-206,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:探讨六神丸配伍复合维生素B对白血病化疗后口腔溃疡的疗效及护理效果。方法:选取2014年8月—2016年8月潜江市中心医院收治的白血病化疗后口腔溃疡患者80例作为研究对象,按照入院顺序,单号作为对照组,双号作为观察组,每组各40例。对照组患者给予呋喃西林漱口水进行口腔护理,观察组患者给予六神丸配伍复合维生素B治疗。观察2组患者口腔溃疡的治疗效果、治疗前后血清微量元素、红细胞免疫状态等指标的变化情况,比较2组患者满意度评分情况。结果:观察组患者的总有效率为90.0%(36/40),明显高于对照组的77.5%(31/40),差异有统计学意义(P<0.05)。观察组患者的护理满意评分显著高于对照组,差异有统计学意义(P<0.05)。治疗后,观察组患者的血清锌、硒、铁水平及免疫指标CD3+、CD8+、自然杀伤细胞水平均显著优于对照组,差异均有统计学意义(P<0.05)。结论:六神丸配伍复合维生素B对白血病化疗后口腔溃疡的疗效较好,能够显著改善患者症状,有助于预后。OBJECTIVE ：To probe into the efficacy and nursing experience of Liushen pills combined with compound vitamin B in treatment of oral ulcer after leukemia chemotherapy. METHODS ： 80 patients with oral ulcer after leukemia chemotherapy admitted into Qianjiang Central Hospital from Aug. 2014 to Aug. 2016 were selected, and according to the order of admission, the single number as the control group, even as the observation group, with 40 cases in each. The control group were treated with Furacilin rinse slobber for oral care, while the observation group were given Liushen pills combined with compound vitamin B. The treatment effects of oral ulcer, changes of serum trace elements before and after treatment and immune function of erythrocytes of two groups were observed. Patients＇ satisfaction scores of two groups were compared. RESULTS ： The total effective rate of observation group was 90. 0% （36/40）, significantly higher than that of control group [ 77. 5% （31/40）~, with statistically significant difference（P 〈 0. 05）. Nursing satisfaction score of observation group was higher than the control group, with statistically significant difference （P 〈 0.05 ）. After treatment, the serum levels of zinc, selenium and iron, immunity indicators of CD3＋ , CD8＋ and NK level in observation group were significantly better than those in control group, with statistically significant difference （P 〈 0. 05 ）. CONCLUSIONS ： The efficacy of Liushen pills combined with compound vitamin B in treatment of oral ulcer after leukemia chemotherapy is significant, which can remarkably improve patients＇ symptoms and contribute to the prognosis.

关 键 词：六神丸 复合维生素B 化疗 口腔溃疡 

分 类 号：R988.2[医药卫生—药品]