电子纤维支气管镜下球囊扩张术治疗结核性支气管狭窄（附52例临床分析）  

Clinical analysis of 52 cases with tuberculous bronchostenosis treated by electronic fiber bronchoscopic balloon dilation

作　　者：杨守峰[1] 苏菲菲[1] 张抱一[2] 戴建义[1] 黄默荷 陈贤豪 李利敏[1] YANG Shou-feng SUFei-fei ZHANG Bao-yi DAIJian-yi HUANG Mo-he CHENXian-hao LI Li-min. Ding- li(Clinical College of Wenzhou Medical University, Infectious Disease Department of Wenzhou Central Hospital, Wenzhou 325000, Chin)

机构地区：[1]温州医学院定理临床学院温州市中心医院感染科,325000 [2]温州医学院定理临床学院温州市中心医院呼吸科,325000

出　　处：《中国防痨杂志》2017年第3期309-311,共3页Chinese Journal of Antituberculosis

基　　金：温州市科技局资助项目（Y20130290）

摘　　要：分析电子纤维支气管镜下球囊扩张术治疗结核性支气管狭窄的疗效.选择温州市中心医院2010年1月至2015年12月收集的52例确诊的支气管结核患者为研究对象,均接受电子纤维支气管镜下球囊扩张治疗,分别测定术前和术后气道狭窄段直径、第一秒用力呼气容积（FEVl）、用力肺活量（FVC）及气促评分,并对6～18个月内随访情况进行评价.结果显示,52例患者术后狭窄段气道直径[（6.71±1.62） mm]较术前[（2.92±0.75） mm]明显增大,差异有统计学意义（t=-25.46,P＜0.01）,94.23％（49/52）的患者治疗后气道直径即刻增大;52例患者术后FEV1和FVC分别为（2.12±0.55）L和（3.58±0.94）L,较术前[分别为（1.57±0.45）L和（2.14±0.61） L]均明显增加,差异均有统计学意义（t值分别为-8.50、-9.77,P值均＜0.01）;气促评分由术前的3～4级降低至术后的2级的患者达69.23％（36/52）.52例患者随访6～18个月,4例患者出现再狭窄,有效率为92.31％（48/52）.作者认为,电子纤维支气管镜下球囊扩张治疗对结核性支气管狭窄疗效显著.To assess the value of electronic fiber bronchoscopic balloon dilation in the treatment of tuberculous bronchial stenosis.Fifty-two patients,who had been confirmed as tuberculous bronchial stenosis at Wenzhou Central Hospital between Jan.2010 and Dec.2015,were recruited in this study.All patients were treated with balloon dilation under bronchoscope,and their airway diameters,dyspnea index were evaluated,and their FEV1 and FVC were tested before and after treatment.After the treatment with balloon dilatations,the airway average diameter （（2.92±0.75） mm vs （6.71±1.62） mm）,FEV1 （（1.57±0.45） L vs （2.12±0.55） L） and FVC （（2.14±0.61） L vs （3.58±0.94） L） in all patients increased significantly （t=-25.46,-8.50,-9.77;P values were all less than 0.01）;and the airway diameter of 94.23% （49/52） patients was immediately increased.The dyspnea index of 69.23% （36/52） patients decreased from level 3-4 to level 2.In 6-18 months follow-up,restenosis occurred in 4 cases.The balloon dilatation is a safe,simple and effective method to treat tuberculous bronchial stenosis.

关 键 词：支气管镜检查 结核 支气管疾病 气管狭窄 气囊扩张术 

分 类 号：R563[医药卫生—呼吸系统]