儿童重症支原体肺炎临床分析  

Clinical Analysis of Severe Mycoplasma Pneumoniae Pneumonia in Children

作　　者：张静[1] 马洪美[2] 侯瑞英[2] 秦凯凯 王彬[1] 

机构地区：[1]潍坊医学院儿科学教研室,山东潍坊261053 [2]潍坊医学院附属医院儿科

出　　处：《潍坊医学院学报》2017年第1期63-65,共3页Acta Academiae Medicinae Weifang

摘　　要：目的探讨、分析重症支原体肺炎(RMPP)的临床资料,为临床早期诊断、治疗提供依据。方法回顾性分析2015年3月~2016年3月100例重症支原体肺炎患儿(观察组)和101例轻症支原体肺炎患儿(对照组)的住院病历资料,汇总年龄、超敏CRP、血沉、心肌酶谱、T淋巴细胞亚群、病程1周及出院前1d的肺炎支原体抗体的临床数据进行分析。结果观察组超敏CRP、血沉、LDH、CD_8^+水平明显高于对照组,观察组CD_3^+,CD_4^+及CD_4^+/CD_8^+水平明显低于对照组,差异有统计学意义(P<0.01)。结论重症支原体肺炎早期检测肺炎支原体抗体假阴性明显,不易于发现。因此,通过对超敏CRP、血沉、心肌酶谱及T淋巴细胞亚群的密切关注对于重症支原体肺炎的预防、诊断、治疗有着重要意义。Objective To investigate and analyze the clinical analysis of severe mycoplasma pneumoniae pneumonia,so as to di- agnose and treat the disease earlier. Methods A retrospective study of children with MPP was performed in 100 severe cases （ observation group） and 100 mild cases （control group） in department of respiratory, from March 2015 to March 2016, including age,Hs-CRP, ESR, Myo- cardial enzymes, blood T-lymphocyte subsets,course of 1 week and 1 day before leaving hospital of mycoplasma pneumoniae antibody, were analysed. Results The percentages of Hs-CRP, ESR, LDH, CD8＋ in observation group were higher than those in control group（ P 〈 0.01 ）. The percentages of T-Lymphocyte subsets CD3 ＋ , CD4 ＋ , CD4 ＋/CD8＋ in observation group were lower than those in control group （ P 〈 0. 01 ） ,the differences were statistically significant. Conclusion Early stage for severe pneumonia mycoplasma detection of mycoplasma pneumoniae antibody false negative,is not easy to find. So close attention to the factors of Hs-CRP, ESR, Myocardial enzymes, blood T-lymphocyte subsets for prevention,diagnosis, treatment of severe mycoplasma pneumonia has important significance.

关 键 词：儿童 支原体肺炎 重症 临床分析 

分 类 号：R563.19[医药卫生—呼吸系统]