红外光谱分析法分析肾鹿角形结石化学成分的效果及其与泌尿系统感染的关系  

The effect of infrared spectral analysis in analyzing of the chemical composition of renal staghorn ;calculi and its relationship with urinary tract infections

作　　者：高永生[1] 张丽[2] 赵晓华[1] 王颖[3] 黄克岭[1] 张长江[1] 李双利[1] 

机构地区：[1]唐山市开滦总医院泌尿外科,063000 [2]唐山市开滦总医院彩超室,063000 [3]唐山市开滦总医院腔镜中心,063000

出　　处：《中国医师进修杂志》2017年第2期131-134,共4页Chinese Journal of Postgraduates of Medicine

摘　　要：目的：探讨红外光谱分析法分析肾鹿角形结石化学成分的效果，并依据成分结果探讨其与泌尿系统感染的关系。方法收集2014年6月至2016年6月收治的186例肾鹿角形结石患者的临床资料，分别采用红外光谱分析法和传统化学滴定法分析结石成分，检测结石感染情况，分析结石感染情况与尿路感染情况及其与结石成分之间的关系。结果红外光谱分析法与化学滴定法在检测肾鹿角形结石成分方面比较差异无统计学意义（P＞0.05）。186例患者中有56例（30.11%）出现结石细菌感染（感染组），130例（69.89%）未发生结石细菌感染（非感染组）。感染组尿常规异常率、尿路感染率、中段尿阳性感染率及棉拭子阳性感染率均显著高于非感染组[73.21%（41/56）比50.77%（66/130）、19.64%（11/56）比3.85%（5/130）、50.00%（28/56）比6.15%（8/130）、67.86%（38/56）比8.46%（11/130）]，差异有统计学意义（P＜0.01）。感染组碳酸磷灰石结石率、六水磷酸镁铵结石率显著高于非感染组[21.43%（12/56）比5.37%（7/130）、57.14%（32/56）比2.31%（3/130）]，差异有统计学意义（P＜0.01）。非感染组草酸钙结石率、尿酸结石率显著高于感染组[50.00%（65/130）比5.36%（3/56）、24.62%（32/130）比1.79%（1/56）]，差异有统计学意义（P＜0.01）。结论采用红外光谱分析法分析由泌尿系统感染引起的肾鹿角形结石成分，简单可靠，易操作，对于做好术后的感染防御工作具有重要意义。Objective To explore the effect of infrared spectral analysis in analyzing of the chemical composition of renal staghorn calculi and its relationship with urinary tract infections. Methods From June 2014 to June 2016, the clinical data of 186 patients with renal staghorn calculi were collected. The stone composition were analyzed by infrared spectroscopy and traditional chemical titration, and the stones infection were detected by microbial analysis system. The relation between stones infection, urinary tract infection and stone composition were analyzed. Results The results of infrared spectroscopy and traditional chemical titration in detecting renal staghorn calculi ingredient had no significant differences （P〉0.05）. In 186 patients, 56 patients （30.11%） was in infected group, and 130 patients （69.89%）was in non-infected group. The abnormal urine rate, urinary tract infection rate, medistream urine positive infection rate and cotton swabs positive infection rate in infected group were was significantly higher than those in non-infected group： 73.21%（41/56） vs. 50.77%（66/130）, 19.64%（11/56） vs. 3.85%（5/130）, 50.00%（28/56） vs. 6.15%（8/130）, 67.86%（38/56） vs. 8.46%（11/130）, P〈0.01. The carbonate apatite stones rate and six water magnesium ammonium phosphate rate in infected group were significantly higher than those in non-infected group： 21.43%（12/56） vs. 5.37%（7/130）, 57.14%（32/56） vs. 2.31%（3/130）, P〈0.01. The calcium oxalate rate and uric acid rate in non-infected group were significantly higher than those in infected group：50.00%（65/130） vs. 5.36%（3/56）, 24.62%（32/130） vs. 1.79%（1/56）, P〈0.01. Conclusions Analysis of staghorn calculi ingredient caused by urinary bacterial infection with infrared spectroscopy is simple, reliable and easy to operate. It is important for postoperative infection prevention.

关 键 词：光谱分析 肾结石 主成分分析 感染 

分 类 号：R692.4[医药卫生—泌尿科学]