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作 者:Wenxiang Zhang Xiaomin Song Feng Ni Jinbao Cheng Bai-Lin Wu Hong Jiang
机构地区:[1]Clinical College of PLA Affiliated Anhui Medical University,Hefei 230031,China [2]Reproductive Medicine Center,the 105^th hospital of PLA,Hefei 230031,China [3]Children's Hospital of Fudan University,Institute of Biomedical Science,Shanghai Medical College of Fudan University,Shanghai,China 200032 [4]Boston Children's Hospital and Harvard Medical School,Boston,MA 02115,USA
出 处:《Science China(Life Sciences)》2017年第3期315-318,共4页中国科学(生命科学英文版)
基 金:supported by the National Natural Science Foundation of China(81501216);Anhui Provincial Natural Science Foundation(1608085MH165);supported in part by the National Basic Research Program of China grants from the Ministry of Science and Technology of China(2013CB945404 and 2010CB529601)
摘 要:Dear Editor,Infertility affects 10%?15%of couples trying to conceive,with male factors contributing to as many as 50%of infertile cases(Meng et al.,2015).Azoospermia or severe oligozoospermia(oligo/azoospermia),clinically characterized by a complete or partial absence of sperm in the ejaculate,Dear Editor,Infertility affects 10%?15%of couples trying to conceive,with male factors contributing to as many as 50%of infertile cases(Meng et al.,2015).Azoospermia or severe oligozoospermia(oligo/azoospermia),clinically characterized by a complete or partial absence of sperm in the ejaculate,account for 10%?15%of male infertility(Wosnitzer et al.,2014).Approximately 20%?30%of men with oligo/azoospermia are attributed to the known genetic factors,
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