自拟颗粒泡洗方治疗急性甲沟炎临床研究  

Keli-Paoxi power for the treatment of acute paronychia

作　　者：王剑平[1] 赵蒙 

机构地区：[1]中国中医科学院望京医院外一科,北京100102 [2]北京市东城区朝阳门社区卫生服务中心,100010

出　　处：《国际中医中药杂志》2017年第3期212-214,共3页International Journal of Traditional Chinese Medicine

摘　　要：目的 评价自拟颗粒泡洗方治疗急性甲沟炎的疗效.方法 将符合入选标准的144例急性甲沟炎患者按随机数字表法分成3组,每组48例.治疗组采用自拟颗粒泡洗方泡洗,对照1组采用莫匹罗星软膏局部涂抹;对照2组采用75%医用酒精泡洗.3组均治疗2周,随访2个月.采用VAS量表评价患者患处触痛,观察3组患者甲沟红肿消退时间,评价临床疗效并记录患者甲沟炎复发率.结果 治疗后,治疗组红肿消退时间[（2.2±0.6）d比（8.1±1.7）d、（7.9±1.2）d,F=344.597]较对照1组、对照2组缩短（P〈0.01）;治疗组VAS评分[（1.2±0.2）分比（3.2±0.3）分、（3.1±0.3）分,F=831.273]低于较对照1组、对照2组（P〈0.01）.治疗组总有效率为100.0%（48/48）、对照1组为83.3%（40/48）、对照2组为81.3%（39/48）,3组比较差异有统计学意义（χ2=9.700,P=0.008）;随访2个月,治疗组复发率为2.1%（1/48）、对照1组为16.7%（8/48）、对照2组为14.6%（7/48）,3组比较差异有统计学意义（χ2=6.000,P=0.049）.结论 自拟颗粒泡洗方可减轻急性甲沟炎患者患处的触痛,促进甲沟红肿消退,降低复发率,提高临床疗效.Objective To evaluate the curative effect of Keli-Paoxi power for the treatment of acute paronychia. Methods A total of 144 patients with acute paronychia were randomly divided into a Keli-Paoxi power group, a mupirocin ointment group and an ethanol soaking group, 48 in each group. All patients were treated for 3 weeks and followed-up for 2 months. The time to regression of redness and swelling in the nail groove was recorded. The Visual Analogue Scale （VAS） was used to assess tenderness. The curative effects were evaluated, and recurrence of paronychia was recorded. Results The time to regression of redness and swelling in the nail groove in the Keli-Paoxi power group （2.2 ± 0.6 d） was significantly shorter than that in the mupirocin ointment group （8.1 ± 1.7 d） or ethanol soaking group （7.9 ± 1.2 d; F=344.597, P〈0.01）. The VAS Scores in the Keli-Paoxi power group （1.2 ± 0.2） was significantly lower than that in the mupirocin ointment group （3.2 ± 0.3） or ethanol soaking group （3.1 ± 0.3; F=831.273, P〈0.01）. The total effective rate in the Keli-Paoxi power group （100.0%, 48/48） was significantly higher than that in the mupirocin ointment group （83.3%, 40/48） or ethanol soaking group （81.3%, 39/48; χ2=9.700, P=0.008）. The recurrence rate of paronychia in the Keli-Paoxi power group （2.1%, 1/48） was significantly lower than that in the mupirocin ointment group （16.7%, 8/48） or ethanol soaking group （14.6%, 7/48; χ2=6.000, P=0.049） at 2 months follow-up. Conclusions Keli-Paoxi power can alleviate tenderness, shorten the time to regression of redness and swelling in the nail groove, decraese recurrence in patients with acute paronychia. The curative effect of Keli-Paoxi power is superior to mupirocin ointment and ethanol soaking in the treatment of acute paronychia.

关 键 词：甲沟炎 急性病 颗粒泡洗方 外用制剂 

分 类 号：R269[医药卫生—中西医结合]