不同产地党参药材及其水提物的红外光谱特征分析  

Infrared spectral characteristics of Codonopsis Radix from different habitats and their aqueous extracts

作　　者：杨波[1] 张娟娟[1] 孙胜杰[1] 王颖莉[1] 

机构地区：[1]山西中医学院,晋中030619

出　　处：《药物分析杂志》2017年第3期438-443,共6页Chinese Journal of Pharmaceutical Analysis

基　　金：山西省科技厅项目(20130313015-2)

摘　　要：目的:对不同产地党参药材及其水提物的红外指纹图谱进行比较分析,说明党参的红外光谱特点。方法:采用傅里叶变换红外光谱(Fourier transform infrared spectroscopy,FTIR)分析方法,采集党参药材及水提物的红外光谱,对光谱进行双指标序列分析。结果:7个产地党参药材的红外图谱在3 385、2 929、2 360、1 734、1 541、1 507、1 456、1 250、870、818、778、668 cm^(-1)附近有12个共有峰,主要对应党参中的多糖、党参苷、内酯类等成分。以陵川党参为对照,得到原药材的平均共有峰率为72.74%,水提物的平均共有峰率为58.54%,其中原药材中壶关党参与陵川党参的关系最为接近。结论:FTIR图谱分析可为党参的鉴定及质量控制提供补充。Objective：To find out characteristics of Codonopsis Radix＇s infrared spectroscopy by comparing and analyzing infrared fingerprints of Codonopsis Radix from different habitats and their aqueous extracts. Methods：Fourier transform infrared spectra of the crude drugs and their aqueous extracts were collected. Then the spectra were processed by dual index sequence analysis. Results：FTIR spectra of Codonopsis Radix from 7 different habitats had 12 common peaks at 3 385,2 929,2 360,1 734,1 541,1 507,1 456,1 250,870,818,778 and 668 cm（-1）,which corresponded to components such as polysaccharides,dangshen glycosides and lactone,etc.With Lingchuan Codonopsis Radix as the control group,the original group＇s common peak ratio received was 72.74%,the aqueous extract group＇s common peak ratio was 58.54%,and Codonopsis Radix of Lingchuan and Huguan had the closest relationship in similarity.Conclusion： The analysis of FTIR spectra could provide supplement for the identification and quality control of Codonopsis Radix.

关 键 词：党参 党参水提物 多糖 党参苷 内酯类 双指标序列分析 

分 类 号：R917[医药卫生—药物分析学]