3～6岁辅助生育技术出生儿童的出生情况和精神运动发育状况分析  

Neonatal Outcome and Psychomotor Development of Children at 3-6 Years Conceived by ART

作　　者：陈小琴[1] 张清学[2] 杨冬梓[2] 赵倩[3] 

机构地区：[1]广州市红十字会医院,广东广州510220 [2]中山大学附属第二医院,广东广州510120 [3]南方医科大学珠江医院,广东广州510282

出　　处：《现代医院》2017年第2期211-213,216,共4页Modern Hospitals

摘　　要：目的初步评价3~6岁辅助生育技术出生儿童的出生情况和精神运动发育情况。方法随访体外受精-胚胎移植出生的3~6岁儿童68例,随机抽取同期自然妊娠出生的3~6岁儿童68例作为对照,比较其出生情况,体格和精神运动发育状况。结果辅助生育技术(IVF/ICSI/FET)出生单胎与自然妊娠出生单胎比较、双胎与自然妊娠出生双胎比较,其出生情况、BMI、发育商的差异均无统计学意义;多因素分析结果显示,孕周、母亲文化程度对发育商的影响有统计学意义,胎数和母亲年龄是早产的影响因素,受孕方式不是影响因素。结论辅助生育技术出生儿童的出生情况和精神运动发育情况与自然妊娠出生儿童无明显差别。Objective To investigate the neonatal outcome and mental development of children of assisted reproduc- tive techniques （ ART ） at 3 - 6 years. Methods A total of 68 IVF/ICSI/FET children, at 3 - 6 years were follow - up visi- ted from February 2011 to February 2013. The control group comprised 68 children, who were naturally borned. The neonatal outcomes, physical and mental development were evaluated. Results There were no significant differences in neonatal out- comes, BMI and developmental quotients （DQs） between two groups of ART children and control, and between two twins, groups. A multivariate regression analysis indicated that gestational age and maternal education had a significant influence on DQs, fetal number and maternal age had a significant influence on premature. The conception mode did not affect DQs. Con- clusion There are no significantly differences in the neonatal outcome and psychomotor development between ART children and normal conception children in this study.

关 键 词：辅助生育技术 出生情况 儿童精神运动发育 

分 类 号：R174[医药卫生—妇幼卫生保健]