空间微重力环境对骨代谢影响的研究进展  

Advances in Research on Effects of Space Microgravity on Bone Metabolism

作　　者：苗治平[1] 仇伍霞 马小莉[1] 骞爱荣[1] 

机构地区：[1]西北工业大学生命学院空间生物实验模拟技术国防重点学科实验室骨代谢研究室,西安710072

出　　处：《宇航学报》2017年第3期219-229,共11页Journal of Astronautics

基　　金：国家自然科学基金(31570940);教育部新世纪人才支持计划(NCET-12-0469)

摘　　要：详细介绍了空间微重力环境对航天员骨代谢影响的国内外研究现状,并总结实验动物和骨组织细胞的太空飞行实验结果以及失重性骨丢失发生的可能机制。介绍了利用新型抗磁悬浮模拟失重技术平台获得的部分细胞实验结果。提出了尚需研发更多新型地基微重力模拟平台来开展骨代谢研究,同时需要更多真实空间飞行机会的进一步验证,为我国空间生物医学的发展建设提供参考。This article not only describes the research on the effects of the space microgravity environment on astronauts＇ bone metabolism at home and abroad,but also summarizes the space flight experiment results from the lab animals and bone cells as well as the possible mechanism of the microgravity-induced bone loss.Moreover,this paper introduces some bone metabolism results using a novel simulated microgravity model,a diamagnetic levitation platform,and proposes to develop much more novel microgravity simulated platforms to further carry out bone metabolism research as well as much more space flight chances to verify the results from the simulated models in future,which provides a reference for space biomedical study in China.

关 键 词：微重力 空间飞行 骨丢失 骨代谢 骨组织细胞 

分 类 号：V7[航空宇航科学技术]