选择性宫内生长受限胎儿静脉导管血流频谱分析  

Study of Doppler blood flow spectrum of ductus venosus in monochorionic diamniotic twins with selective intrauterine growth restricted

作　　者：张兴[1] 李淑娟[1] 巴宏军[1] 李轩狄[1] 王慧深[1] 

机构地区：[1]中山大学附属第一医院心血管儿科,广州510080

出　　处：《中华超声影像学杂志》2017年第3期238-242,共5页Chinese Journal of Ultrasonography

基　　金：教育部博士点博导基金（20130171110048）

摘　　要：目的研究不同类型单绒毛膜双羊膜囊双胎选择性宫内生长受限（sIUGR）胎儿静脉导管血流频谱特征。方法选取35例sIUGR孕妇作为研究对象，其中Ⅰ型sIUGR10例，Ⅱ型sIUGR13例，Ⅲ型sIUGR12例，每1例sIUGR按孕周匹配1例正常单胎作为对照组。分别测量静脉导管S波、D波、A波血流峰值及搏动指数（DV-PI）、前负荷指数（DV-PLI）及S／A。结果①Ⅰ、Ⅱ、Ⅲ型sIUGR大胎及I型sIUGR小胎静脉导管血流频谱与对照组比较，差异均无统计学意义（均P〉0．05）。②Ⅱ型和Ⅲ型sIUGR小胎静脉导管搏动指数（DV-PI）、前负荷指数（DV-PLI）及S／A显著高于对照组，差异均有统计学意义（均P〈0．05）；静脉导管S波、D波血流峰值与对照组比较，差异均无统计学意义（均P〉0．05）。结论Ⅰ、Ⅱ、Ⅲ型sIUGR大胎及Ⅰ型sIUGR小胎静脉导管血流频谱基本正常，Ⅱ型和Ⅲ型sIUGR小胎静脉导管前向阻力增加、心脏舒张功能降低，需密切监测。Objective To evaluate Doppler spectrum of ductus venosus（DV） in selective intrauterine growth restricted（sIUGR） pregnancies. Methods Thirty five sIUGR pregnancies and 35 normal single pregnancies with same gestational week were enrolled, there were 10 sIUGR Ⅰ , 13 sIUGR Ⅱ and 12 sIUGR Ⅲ in sIUGR. Spectrum of ductus venosus, such as DV-S wave, DV-D wave, DV-A wave, DV-PI, DV-PLI and S/A were assessed. Results （1） There was no significantly difference in spectrum of ductus venosus between bigger of sIUGR, smaller of sIUGR Ⅰ with normal fetus （all P 〉0.05）. （2） Compared with normal fetus,DV-PI,DV-PLI and S/A were significant higher in smaller of sIUGR Ⅱ and sIUGRⅢ（ P 〈0.05）; DV-S wave, and DV-D wave showed no significantly difference in smaller of sIUGR Ⅱ and sIUGR Ⅲ （ P 0.05）. Conclusions Spectrum of ductus venosus in bigger of sIUGR and smaller of sIUGR Ⅰ are mainly normal,and nearly in good condition in utero, inversely, abnormal spectrum of ductus venosus commonly exists in smaller of sIUGR Ⅱ and sIUGR Ⅲ , and supervision should be done carefully in these group.

关 键 词：超声检查 产前 胎儿生长迟缓 静脉导管 血流频谱 

分 类 号：R445.1[医药卫生—影像医学与核医学] R714.5[医药卫生—诊断学]