营养化学感应系统研究进展  

Progress on nutrient chemosensory system

作　　者：何庆华[1] 李铁军[2] 阳成波[2] 印遇龙[2] HE Qing-hua LI Tie-jun YANG Cheng-bo YIN Yu-long(Department of Food Science and Engineering, College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, Guangdong 518060, China Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Key Laboratory of Agro-Ecological Processes in Subtropical Region, Hunan Provincial Engineering Research Center of Healthy Livestock, Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Changsha, Hunan 410125, China)

机构地区：[1]深圳大学化学与环境工程学院食品科学与工程系,广东深圳518060 [2]中国科学院亚热带农业生态研究所中国科学院亚热带农业生态过程重点实验室/湖南省畜禽健康养殖工程技术中心/农业部中南动物营养与饲料科学观测实验站,湖南长沙410125

出　　处：《农业现代化研究》2017年第2期322-327,共6页Research of Agricultural Modernization

基　　金：国家重点基础研究发展计划(973)项目(2013CB127301);国家自然科学基金项目(31101729;31301989)~~

摘　　要：人和动物消化器官的营养化学感应系统是胃肠上皮细胞受体对食物信息感受与内脏迷走神经元之间信息传递和互作的复杂信号传递系统。营养化学感应系统由独立化学感应细胞组成,具有形态学的多样性,在体内分布十分广泛,这为其功能作用的发挥奠定了基础。研究表明,营养化学感应系统在调控采食、消化与吸收、肠道生长与功能、肠道防御机制以及宿主与微生物的互作中起着重要作用,并且不同细胞型之间具有不同的功能。它们是营养物质消化吸收的重要调控途径,其功能研究有助于化学感应机制的营养学作用的理解。因此,为了更好的理解和研究营养化学感应系统,本文就营养化学感应系统的分布及其功能作用进行了简要综述。The nutrient chemosensory system of human and animal digestive organs is a complex signaling transduction system, where the information transfers and interacts between nutrient sensory receptors in the gastrointestinal epithelial cell and visceral afferent neurons. Chemosensory system is composed by solitary chemosensory cells. It not only widely distributes in body, but also has a morphological diversity. It laid the foundation for its function. Studies showed that it is crucial to the action mechanisms of chemosensory system in the regulation of feeding, digestion and absorption, growth and intestinal function, intestinal defense as well as host-microbe interaction. Moreover, different cell types have different functions. In short, the chemosensory system in human and animal is an important regulatory pathway for nutrient digestion and absorption. These studies are crucial to understand nutritional functions of chemosensory mechanisms. Therefore, in order to better understand and study chemosensory system, its distribution and functions are briefly reviewed in this paper.

关 键 词：营养化学感应 独立化学感应细胞 味觉受体 激素分泌 采食调控 消化道 

分 类 号：S852.2[农业科学—基础兽医学]