胰腺动静脉畸形的诊治  

Diagnosis and treatment of pancreatic arteriovenous malformation

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作  者:高鹏骥[1] 陈雷[1] 冷希圣[1] 朱继业[1] 

机构地区:[1]北京大学人民医院肝胆外科,100044

出  处:《中华普通外科杂志》2017年第3期215-219,共5页Chinese Journal of General Surgery

摘  要:目的探讨胰腺动静脉畸形的临床特点及治疗方法。方法收集文献报道的和我们诊治过的胰腺动静脉畸形患者的临床资料,对患者的发病年龄、性别、病变部位、临床表现和治疗方法进行总结。结果共有95例患者纳入了研究,其中男83例(87.37%),女12例(12.63%),平均年龄50.41±9.76岁。就诊原因以腹痛(45.26%)最为多见,其他包括黑便(17.89%)、腹痛伴黑便(14.74%)、呕血(8.42%)、黄疸(1.08%),12例患者无明显症状。并发症包括:消化道出血(48。42%),胰腺炎(23,16%),十二指肠溃疡(16.84%),门静脉高压症食管胃静脉曲张(11.58%),胰腺假性囊肿囊内出血(4.21%),胆道出血(3.16%)。58例病变(61.05%)位于胰头部,19例(20%)位于胰体尾部,13例(13.68%)为多发病灶。49例(51.58%)患者接受了手术治疗,17例(17.89%)栓塞治疗,其中7例(7.37%)栓塞后行手术治疗,2例(2.11%)栓塞治疗失败后行放疗,4例(4.21%)放疗,19例未实施治疗。结论胰腺动静脉畸形多见于中年男性,腹痛和消化道出血是最常见的临床表现.有症状的患者应考虑手术治疗。Objective To discuss the clinical presentation and management of pancreatic arteriovenous malformation. Methods The data pool for the analysis was collected from pancreatic arteriovenous malformation cases encountered by our hospital and sporadic case reports in the literature. Results A total of 95 cases were collected, including 83 males (87.37%) and 12 females ( 12. 63% ). The most common presenting symptom was epigastric pain (45.26%), followed by melena ( 17.89% ), epigastric pain accompanied melena (14. 74% ) and haematemesis (8.42%). The most commonly associated complications were gastrointestinal bleeding (48.42%), pancreatitis (23.16%) , duodenal ulcer (16. 84% ), portal hypertension (11.58%), pseudocyst (4. 21% ) and hemobilia (3.16%). Most cases were of singular lesion, located in the pancreatic head (61.05 % ) in 58 cases and in the pancreatic body-tail (20%) in 19 cases. Surgery (51.58%) was the most common treatment for pancreatic arteriovenous malformation cases, followed by transarterial embolization (17.89%), a combination of surgery and transarterial embolization (7.37%) and radiotherapy (4. 21% ). Watchful conservation was adopted in 20% cases. Conclusions Pancreatic arteriovenous malformation occurs most commonly in males. Epigastric pain and gastrointestinal bleeding are the main clinical presentations. Surgical resection is indicated in symptomatic patients.

关 键 词:胰腺 动静脉畸形 消化道出血 

分 类 号:R657.5[医药卫生—外科学]

 

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