藤壶附着:从基底探测到胶的固化  

Barnacle Adhesion:From Substrate Detection to Cement Curing

作　　者：张欣康[1] 刘兴平[1] 曾玲[1] 叶宗煌 胡碧茹[1] 吴文健[1] 

机构地区：[1]国防科学技术大学理学院,长沙410073

出　　处：《生物化学与生物物理进展》2017年第3期204-214,共11页Progress In Biochemistry and Biophysics

摘　　要：藤壶在水下设施上的牢固黏附一方面造成极大的污损和危害,另一方面为水下的牢固粘接提供了灵感.相关的防污和水下超粘接等技术的解决强烈依赖于对其附着过程及分子机制的理解.目前,对藤壶黏附的宏观过程已有了较为深入的了解,主要包括基底探测、信号传导、胶液分泌以及胶的固化,但对该过程中作用的分子机制如受体蛋白的识别、基因表达的调控以及胶蛋白的交联固化的研究依然有限,而上述任何阶段的干扰都可为防污或水下粘接提供重要的理论指导.因此,深入理解各阶段的相关分子机制对防污和水下粘接至关重要.本文综述了近年来对藤壶附着的相关进展,介绍附着过程中的内部信号分子响应以及胶液分泌过程中的固化交联机制,指出了存在的问题,并提出进一步可能的研究要点.The strong adhesion of barnacles to underwater facilities causes great fowling, on the other hand, it provides a platform for underwater attachment research. The associated anti-fouling and underwater adhesion techniques are strongly dependent on the understanding of their attachment processes and molecular mechanisms. At present, the macroscopic process of the adhesion of the barnacles has a more in-depth development, including the substrate detection, signal transmission, glue secretion and curing, but the molecular mechanism of the process such as receptor recognition and the regulation of gene are still limited. Biological and biochemical studies have been motivated mainly by understanding the nature of the adhesion, which indicate that the various stages of molecular mechanisms related to anti-fouling and adhesion is essential. In this paper, the focuses are on the common themes and interconnections in three related areas： the process of barnacle attachment, the internal signal molecular response during adhesion, and the mechanism of curing during the process of glue secretion. The existing problems were also given to analyze further possible research.

关 键 词：藤壶 基底探测 信号通路 胶分泌与固化 

分 类 号：Q819[生物学—生物工程]