血管内超声结合血流储备分数对不稳定型心绞痛患者冠状动脉临界病变介入治疗的指导价值  

Effect of intravascular ultrasound combined with fractional flow reserve on guiding interventional treatment for critical coronary disease in patients with unstable angina pectoris

作　　者：李松[1] 吴志华 林茴[1] 吴剑胜[1] 张东辉[1] 

机构地区：[1]深圳市第四人民医院,广东深圳518033

出　　处：《岭南心血管病杂志》2017年第1期52-55,共4页South China Journal of Cardiovascular Diseases

摘　　要：目的研究血管内超声(intravascular ultrasound,IVUS)联合血流储备分数(fractional flow reserve,FFR)检查对于不稳定型心绞痛(unstable angina,UA)患者冠状动脉临界病变介入治疗的临床指导价值。方法收集2013年3月至2014年12月期间,深圳市第四人民医院收治的冠状动脉造影(CAG)证实为UA冠状动脉临界病变患者62例,根据FFR及IVUS检查结果指导临床治疗。结果 62例患者中,22例FFR≤0.75实施经皮冠状动脉介入(PCI)治疗,23例FFR>0.75且IVUS检查提示存在不稳定性斑块患者接受他汀类药物强化治疗,17例FFR>0.75且IVIS显示稳定性斑块患者接受药物保守治疗。3组的主要心血管事件(MACE)发生率比较,差异无统计学意义(P>0.05)。结论 FFR结合IVUS对于判断UA冠状动脉临界病变患者是否需要实施经皮冠状动脉介入治疗具有重要指导意义,能够避免不必要的介入操作,改善临床预后。Objectives To investigate the effect of intravascular ultrasound（IVUS）combined with fractional flowreserve（FFR）on guiding interventional treatment for critical coronary disease in patients with unstable angina pectoris（UAP）.Methods Fome March 2013 to December 2014,62 patients with borderline lesions of UAP in The FourthPeople′s Hospital with coronary angiography（CAG）confirmed were collected,all received clinical treatment based onFFR and IVUS findings.Results In the 62 patients,22 cases with FFR≤0.75 implemented percutaneous coronaryintervention（PCI）treatment,23 cases with FFR 0.75 and IVUS examination revealed the presence of plaque instabilityaccepted statin intensive treatment,17 cases with FFR 0.75 and IVIS displayed unstable plaque received conservativetreatment.Differences of incidence of major adverse cardiovascular events（MACE）among the three groups were notstatistically significant（P〉0.05）.Conclusions FFR combining with IVUS to determine whether UAP critical coronarylesions need to implement PCI treatment has important guiding significance,can avoid unnecessary interventionalprocedures,improve clinical outcomes.

关 键 词：不稳定型心绞痛 冠状动脉临界病变 血管内超声 血流储备分数 临床疗效 

分 类 号：R541.4[医药卫生—心血管疾病]