495例棘球蚴病病例特征分析  

Analysis of characteristics of 495 cases with hydatid disease

作　　者：冯宇[1] 王东[1] 李凡[1] 张颋[2] 胡薇[2] 格鹏飞[1] FENG Yu WANG Dong LI Fan ZHANG Ting HU Wei GE Peng-fei(Gansu Provincial Center for Disease Control and Prevention Lanzhou, Gansu 730020, Chin)

机构地区：[1]甘肃省疾病预防控制中心,兰州730020 [2]中国疾病预防控制中心寄生虫病预防控制所/世界卫生组织疟疾血吸虫病和丝虫病合作中心/卫生部寄生虫病原与媒介生物学重点实验室,上海200025

出　　处：《疾病预防控制通报》2017年第1期55-58,共4页Bulletin of Disease Control & Prevention(China)

基　　金：甘肃省科技支撑计划(1304FKCA120);卫生部病原与媒介重点实验室开放课题(WSBKTKT201305);中国疾病预防控制中心青年基金(2013A103)

摘　　要：目的分析甘肃省棘球蚴病病例特征,为人群棘球蚴病筛查和诊断提供参考。方法分析2014—2015年甘肃省棘球蚴病流行调查中发现的495例棘球蚴病病例特征,用Spss 20.0软件进行描述性分析。结果 495例棘球蚴病病例分布于55个县(区),以细粒棘球蚴病流行为主、占97.98%,多房棘球蚴病占2.02%;病例平均年龄52岁,男女性别比为1∶1.12,汉族(占60.00%)、藏族(占39.94%)、农民(占60.20%),以及文化程度低者(文盲占39.80%、小学占39.39%)是该病的重点人群;B超影像特征显示,485例细粒棘球蚴病例以感染早期的CL型(37.73%)和CEⅠ型(35.46%)居多,10例多房棘球蚴病例在各型均匀分布,病例中以单包囊为主(占79.39%),病灶直径小于8 cm(占84.24%)居多,以单个脏器寄生为主,侵犯的主要脏器为肝脏,单纯肝脏寄生病例占总病例的95.15%。结论甘肃省棘球蚴病分布广泛,应针对重点人群开展人群筛查和健康教育;加强基层筛查人员B超和免疫学检测技术培训,提高对感染病例的早期发现及进行鉴别诊断的能力,开展多种途径的病人发现模式,提高腹部以外脏器感染病人的检出率。Objective To analyze the characteristic of cases with echinococcosis and to provide the reference to screening and diagnosis of the disease in human. Methods There were 495 cases found in the investigation on epidemic status of echinococcosis in Gansu province from 2014 to 2015. The characteristics of the cases were analyzed with Spss 20.0. Results The 495 cases with echinococcosis distributed in 55 counties. Echinococcosis granulosus was the dominant, accounting for 97.98%, while Echinococcosis multilocularis occupied 2.02%. The average age of the cases was 52 years, with sex ratio of male to female of 1∶1.12. The cases concentrated on the nationality of Han（60.00%） and Tibetans（39.94%）, farmers（60.20%）, low cultural degree（39.80% of illiteracy and 39.39% of primary degree）. B-ultrasound image showed that, out of the 485 cases of E. granulosus, most cases were at early infection stage of CL type（37.73%） and CEⅠ type（35.46%）. There were 10 cases with E. multilocularis distributing evenly in each type, with the single cyst infection accounting for 79.39%,and 84.24% of lesion diameter less than 8 cm. Most cases displayed single organ infection, and liver was the predominant infection locus, accounting for 95.15%. Conclusions Echinococcosis widely distributes in Gansu province. Screening and health education should be taken in the major population. B-ultrasound and immunological detection technology training on the staff at the basic level should be strengthened to improve the ability in early diagnosis and differential diagnosis. A variety of ways to find patients should also be developed, to improve the detection rate of infections outside the abdomen.

关 键 词：棘球蚴病 病例 分布 

分 类 号：R532.32[医药卫生—内科学]