我国一般人群血液中锑元素含量调查  

The content of antimony in blood of general population in China

作　　者：潘兴富[1] 丁春光[1] 潘亚娟[1] 张爱华[2] 吴邦华[2] 黄汉林[2] 朱醇[3] 刘徳晔 朱宝立[3] 许光 邵华 郑玉新[1] 闫慧芳[1] PAN Xing-fu DING Chun-guang PAN Ya-juan ZHANG Ai-hua WU Bang-hua HUANG Han-lin ZHU Chun LIU De-ye ZHU Bao-li XU Guang SHAO Hua ZHENG Yu-xin YAN Hui-Jhng(National Institute of Occupational Health and Poison Control, China CDC, Beijing 100050 China)

机构地区：[1]中国疾病预防控制中心职业卫生与中毒控制所化学污染与健康安全重点实验室,北京100050 [2]广东省职业病防治院,广东广州510300 [3]江苏省疾病预防控制中心,江苏南京210009 [4]山东省卫生与职业病防治研究院,山东济南250062

出　　处：《工业卫生与职业病》2017年第2期89-92,95,共5页Industrial Health and Occupational Diseases

基　　金：卫生部行业公益项目(201402021);卫生部行业科研专项(200802020)

摘　　要：目的了解我国一般人群血液中锑元素的含量水平,并分析其人群分布特点,建立我国一般人群生物样本中锑元素含量参考值和横断面基础数据。方法在2009-2010年间采用分层抽样的方法,从东、中、西部3个地区抽取8个省(自治区、直辖市),共完成18 120名调查对象的全血样品的采集。应用电感藕合等离子体质谱法检测血液中锑元素的含量,比较分析我国一般人群血液中锑元素含量在不同年龄、性别中的分布特征。结果我国一般人群血液中锑元素含量中位数为3.46μg/L,其中男性为3.42μg/L,女性为3.48μg/L,在性别间的差异无统计学意义(χ2=2.62;P>0.05)。锑元素含量随年龄增长呈下降趋势且差异有统计学意义(χ2=35.98;P<0.01)。我国人群血液中锑元素含量明显高于国外相关报道。结论自大样本测定、提供了我国一般人群中锑元素含量的可靠数据,也是评估环境污染的一个参考。Objective To investigate the levels of antimony elements in the general population blood in China,understand the population distribution,and establish content reference value in the general population and cross-sectional data of biological samples.Methods A cross-sectional study was performed on 18120 subjects with from 6to 60years-old of 24 regions among 8provinces from 2009 to 2010.The subjects were recruited by stratification sampling method from China.The environmental and physical condition characteristics were collected from a questionnaire,and urine samples were collected at the mean time.The levels of blood antimony were measured using ICP-MS.Data were analyzed by statistics.to compare the distribution characteristics of blood antimony in age and gender.Results Totally,the median of blood antimony were 3.46μg/L.And the male was 3.42μg/L,the female was 3.48μg/L,respectively.There was no statistically significant difference in blood antimony levels between the males and the females（χ2= 2.62,P 0.05）.And there was statistically significant difference in blood antimony levels among age groups（χ2=35.98;P 0.01）,and showed a decreasing trend with age increase.Conclusions The levels of blood antimony in general population in China from present study will provide scientific and reliable reference data for further scientific research.

关 键 词：全血 锑 现况研究 

分 类 号：R111[医药卫生—公共卫生与预防医学]