PVP与PKP治疗骨质疏松脊柱压缩性骨折的临床治疗效果比较  

Comparative Study of the Clinical Effect of PVP and PKP in the Treatment of Osteoporotic Vertebral Compression Fracture

作　　者：张国华[1] 杜伟[1] 罗鹏明[1] 王新虎[1] 王建顺[1] 

机构地区：[1]宝鸡市中心医院脊柱外科,陕西宝鸡721008

出　　处：《现代生物医学进展》2017年第5期909-912,共4页Progress in Modern Biomedicine

摘　　要：目的:分析PKP(即经皮椎体后凸成形术)和PVP(即经皮椎体成形术)在骨质疏松性椎体压缩骨折治疗中的临床应用效果。方法:回顾并抽取我院骨科诊治的164例骨质疏松脊柱压缩性骨折患者资料,根据术式分为PKP组和PVP组各82例,对比分析不同手术前各组VAS评分(即视觉模拟评分法)、ODI(即Oswestry功能障碍指数)、椎体高度以及Cobb角变化,同时对2种手术的安全性进行客观评价。结果:手术后,两组VAS评分、ODI、椎体高度以及Cobb角度均出现明显恢复(P<0.05),在术后相同时间点,PKP组VAS分数、ODI分数、椎体高度、Cobb角度均显著优于PVP组(P<0.05);PKP组手术不良事件发生率(17.07%)显著低于PVP组(36.59%),P<0.05,组间差异明显。结论:PVP、PKP虽然均能够对骨质疏松脊柱压缩性骨折达到修复椎体高度、止痛的治疗效果,但是PKP治疗后椎体恢复情况、手术安全性显著优于PVP。Objective： To analyze the clinical effect of percutaneous kyphoplasty（PKP） and percutaneous vertebroplasty（PVP） in the treatment of osteoporotic vertebral fractures. Methods： The clinical data of 164 cases of osteoporotic vertebral compression fracture for orthopedic diagnosis and treatment was taken for retrospective analysis. According to the surgical group, they were divided into the PVP group and PKP group（82 cases in each group）. The changes of VAS score（ie, visual analogue scale law）, ODI（ie, Oswestry Disability index）, vertebral height and Cobb angle of different surgeries were taken for comparative analysis, while the two kinds of surgical safety were taken for objective evaluation. Results： After surgery, the VAS score, ODI, vertebral height and Cobb angle all showed apparent recovery（P〈0.05）. At the same time point after surgery, the VAS scores, ODI score, vertebral height and Cobb angle of PKP group were significant better than those of the PVP group（P〈0.05）. The occurrence rate of adverse events in PKP group was 17.07%, which was significantly lower than 36.59% in the PVP group, and the difference was statistically significant（P〈0.05）. Conclusion： PVP and PKP both can repair vertebral height and reduce pain treatment for osteoporotic spinal compression fracture, but vertebral body recovery and surgery safety of PKP treatment were significantly better than PVP.

关 键 词：骨质疏松症 脊柱压缩性骨折 经皮椎体成形术 经皮椎体后凸成形术 

分 类 号：R683[医药卫生—骨科学]