辽宁省2011-2013年新报告HIV/AIDS病人中新发感染情况分析  

Status of new infection among the reported HIV/AIDS cases in Liaoning province from 2011 to 2013

作　　者：马宁[1] 康续 周丹[1] 赵砚[1] 鄂爽[1] 周金玲[1] 王莉[1] 姚文清[1] Ma Ning Kang Xu Zhou Dan Zhao Yan E Shuang Zhou Jinling Wang Li Yao Wenqing(Liaoning Provincial Center for Disease Control and Prevention, Liaoning, Shenyang, 110005, China)

机构地区：[1]辽宁省疾病预防控制中心,沈阳110005

出　　处：《中国艾滋病性病》2017年第1期36-39,共4页Chinese Journal of Aids & STD

摘　　要：目的了解辽宁省新报告艾滋病病毒(HIV)感染者/艾滋病(AIDS)病人(简称HIV/AIDS病人)中,HIV新发感染情况,分析其相关影响因素。方法辽宁省2011年4-6月和2012年4月至2013年底,"艾滋病综合防治信息系统"报告的HIV/AIDS病人,收集其血清和血浆样本,进行BED HIV-1捕获酶联免疫法检测,计算新发感染比例,进行!2检验和多因素Logistic回归分析。结果辽宁省2011-2013年的新发感染比例为27.8%,各年分别为27.2%、30.1%、26.5%。新发感染者和既往感染者在年龄、文化程度、婚姻状况、职业、传播途径和样本来源变量上差异均有统计学意义(P<0.05)。多因素分析显示,≤30岁比>30岁更可能是新发感染[比值比(OR)=1.521,95%可信区间(CI)=1.287~1.799];样本来源中与其他就诊者相比,专题调查(OR=2.615,95%CI=1.838~3.719)、无偿献血人员(OR=2.239,95%CI=1.526~3.283)、检测咨询(OR=1.946,95%CI=1.567~2.417)、性病门诊(OR=1.694,95%CI=1.287~2.229)和羁押人员体检(OR=1.455,95%CI=1.104~1.918)更容易发现HIV新发感染者。结论辽宁省艾滋病新报告病例新发感染比例约为1/4左右,结合其相关影响因素,制定有效的防制措施,阻止艾滋病的传播。Objective To understand the status of new infection among the reported HIV/AIDS cases in Liaoning province.Methods Data was obtained from the HIV information system of Liaoning province during 2011-2013,and the serum or plasma samples were collected for the test with BED HIV-1Incidence EIA to know the proportion of new HIV infection.Chi square test and multivariate logistic regression were used for the analysis.Results From 2011 to 2013,the proportion of new infection were 27.2%,30.1%,and 26.5% respectively.Difference between the new infections and those infected in the past were statistically significant（P﹤0.05）with the influencing factors such as age,education,marital status,occupation,transmission route and sample resources.Multifactor analysis showed that those younger than 30 years old were more likely to be new infection（OR=1.521,95% CI=1.287-1.799）.Samples from special survey（OR=2.615,95% CI=1.838-3.719）,blood donors（OR=2.239,95% CI=1.526-3.283）,VCT clinics（OR=1.946,95% CI=1.567-2.417）,STD clinics（OR=1.694,95% CI=1.287-2.229）and detainees（OR=1.455,95% CI=1.104-1.918）were more likely to be new infection.Conclusion There is a high proportion of new infection in Liaoning province.Effective measures should be taken to prevent AIDS spreading based on the related factors.

关 键 词：艾滋病病毒感染者/艾滋病病人 新发感染 BED方法 

分 类 号：R512.91[医药卫生—内科学] R373.9[医药卫生—临床医学]