医学营养治疗对妊娠期糖尿病孕妇妊娠结局的影响  

Effect of medical nutrition therapy on pregnancy outcomes of pregnant women with gestational diabetes mellitus

作　　者：李雪莲[1] 汪洋[1] 刘琼芬[1] 戴婉波[1] 李学文[1] 罗永红[1] 初晓丽[1] 

机构地区：[1]广州医科大学附属深圳沙井医院妇产科,广东深圳518104

出　　处：《中国妇幼保健》2017年第6期1165-1167,共3页Maternal and Child Health Care of China

摘　　要：目的探讨医学营养治疗(MNT)对妊娠期糖尿病(GDM)孕妇妊娠结局的影响。方法根据干预方式将100例GDM孕妇分为观察组与对照组,观察组接受MNT治疗,对照组患者接受常规饮食干预治疗。两组患者随访直至分娩结束,对比两组患者的疗效。结果 1两组患者治疗前空腹血糖(FPG)、口服葡萄糖耐量试验-1h血糖(OGTT-1h PG)、OGTT-2h血糖(OGTT-2h PG)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)相比差异无统计学意义(P>0.05)。观察组与对照组患者治疗后FPG、OGTT-1h PG、OGTT-2h PG、TG均显著下降(P<0.05),两组患者TC、HDL-C、LDL-C在治疗后均无显著变化(P>0.05)。观察组治疗后FPG、OGTT-1h PG、OGTT-2h PG、TG显著低于对照组(P<0.05),两组患者治疗后TC、HDL-C、LDL-C相比差异均无统计学意义(P>0.05)。2观察组胎膜早破发生率显著低于对照组(P<0.05),两组患者巨大儿、羊水过少或过多、早产、新生儿吸入综合征、新生儿高胆红素血症、低体重儿等不良妊娠结局总发生率相比差异无统计学意义(P>0.05)。结论 MNT有利于改善GDM患者的糖脂代谢紊乱,从而进一步改善妊娠结局。Objective To explore the effect of medical nutrition therapy（MNT） on pregnancy outcomes of pregnant women with gestational diabetes mellitus（GDM）.Methods A hundred pregnant women with GDM were divided into observation group and control group according to the intervention methods.The patients in observation group were treated by MNT,while the patients in control group were treated by routine dietary intervention.The patients in the two groups were followed up until the end of delivery,the effects in the two groups were compared.Results There was no statistically significant difference in the levels of fasting blood glucose（FPG）,oral glucose tolerance test-one-hour blood glucose（OGTT-1h PG）,OGTT-two-hour blood glucose（OGTT-2h PG）,triglyceride（TG）,total cholesterol（TC）,high density lipoprotein cholesterol（HDL-C）,low density lipoprotein cholesterol（LDL-C） between the two groups（P〉0.05）.After treatment,the levels of FPG,OGTT-1h PG,OGTT-2h PG,and TG in the two groups decreased significantly（P〈0.05）,but there was no statistically significant difference in the levels of TC,HDL-C,and LDL-C（P〉0.05）.After treatment,the levels of FPG,OGTT-1h PG,OGTT-2h PG,and TG in observation group were statistically significantly lower than those in control group（P〈0.05）,but there was no statistically significant difference in the levels of TC,HDL-C,and LDL-C（P〉0.05）.The incidence rate of premature rupture of fetal membranes in observation group was statistically significantly lower than that in control group（P〈0.05）.There was no statistically significant difference in the incidence rates of macrosomia,oligohydramnios or polyhydramnios,premature birth,neonatal aspiration syndrome,neonatal hyperbilirubinemia,low birth weight,and other adverse pregnancy outcomes between the two groups（P〉0.05）.Conclusion MNT is beneficial to improve the disorder of glucose and lipid metabolism in GDM patients,so as to improve the pregnancy outcome.

关 键 词：医学营养治疗 妊娠期糖尿病 糖脂代谢紊乱 妊娠结局 

分 类 号：R714.256[医药卫生—妇产科学]